| |
RDI ≥ 85%
|
RDI < 85%
|
OR (95% CI)
|
P value
|
|---|
|
(N = 123)
|
(N = 36)
|
|---|
|
As continuous variables
| | | | |
|
IL-6 (pg/ml)
|
2.7 (3.15)
|
5.7 (7.95)
|
1.14 (1.04–1.25)
|
0.006
|
|
D-dimer (μg/ml)
|
0.7 (0.58)
|
1.1 (0.57)
|
2.32 (1.27–4.24)
|
0.006
|
|
CRP (μg/ml)
|
5.3 (7.42)
|
6.4 (9.07)
|
1.02 (0.97–1.06)
|
0.47
|
|
As categorical variables
| | | | |
|
IL-6
|
|
Q 1, 2, 3
|
98 (79.7%)
|
22 (61.1%)
| | |
|
Q4
|
25 (20.3%)
|
14 (38.9%)
|
2.49 (1.12–5.56)
|
0.02
|
|
D-Dimer
|
|
Q 123
|
97 (78.9%)
|
18 (51.4%)
| | |
|
Q4
|
26 (21.1%)
|
17 (48.6%)
|
3.52 (1.60–7.78)
|
0.002
|
|
CRP
|
|
Q 123
|
94 (76.4%)
|
26 (72.2%)
| | |
|
Q 4
|
29 (23.6%)
|
10 (27.8%)
|
1.25 (0.53–2.89)
|
0.61
|
|
IL-6 or D-dimer combinationa
|
|
0
|
79 (86.8%)
|
12 (13.2%)
| | |
|
1 or 2
|
44(64.7%)
|
24 (35.3%)
|
3.59 (1.64–8.87)
|
0.001
|
- Continuous variables are presented as mean (SD) and categorical variables as N (%)
-
RDI relative dose intensity, CRP C-reactive protein
-
aIL-6 or D-dimer combination: 0 = both markers in lower three quartiles; 1 = 1 of the markers in the 4th quartile; 2 = 2 of the markers in the 4th quartile
