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Table 4 Association of stem cell markers with breast density, adjusted for epithelial/stromal tissue, regression coefficient (standard error) for dense vs. non-dense area

From: Tissue-based associations of mammographic breast density with breast stem cell markers

Marker Expression measurea Unadjusted Adjusted for percentage epithelium Adjusted for percentage epithelium and stroma Adjusted for percentage stroma
CD44
 Staining extent 0.95 (0.14)* 0.01 (0.09) −0.29 (0.14) 0.30 (0.26)
 Expression score (extent x intensity) 0.89 (0.14)* −0.04 (0.10) −0.25 (0.16) 0.35 (0.26)
CD24
 Staining extent 0.44 (0.29) 0.12 (0.30) −1.36 (0.43)* −0.65 (0.48)
 Expression score (extent x intensity) 0.37 (0.29) 0.09 (0.30) −1.45 (0.46)* −0.75 (0.49)
ALDH1A1
 Staining extent 0.97 (0.40)* 0.65 (0.40) −0.31 (0.71) 0.18 (0.76)
 Expression score (extent x intensity) 1.11 (0.41)* 0.95 (0.40)b 0.48 (0.63) 0.61 (0.74)
  1. ALDH1A1 aldehyde dehydrogenase family 1 member A1
  2. aAll markers transformed using square root and put on one standard deviation scale
  3. *Significant at 0.05