Table 4 Association of stem cell markers with breast density, adjusted for epithelial/stromal tissue, regression coefficient (standard error) for dense vs. non-dense area
From: Tissue-based associations of mammographic breast density with breast stem cell markers
Marker Expression measurea | Unadjusted | Adjusted for percentage epithelium | Adjusted for percentage epithelium and stroma | Adjusted for percentage stroma |
|---|---|---|---|---|
CD44 | ||||
 Staining extent | 0.95 (0.14)* | 0.01 (0.09) | −0.29 (0.14) | 0.30 (0.26) |
 Expression score (extent x intensity) | 0.89 (0.14)* | −0.04 (0.10) | −0.25 (0.16) | 0.35 (0.26) |
CD24 | ||||
 Staining extent | 0.44 (0.29) | 0.12 (0.30) | −1.36 (0.43)* | −0.65 (0.48) |
 Expression score (extent x intensity) | 0.37 (0.29) | 0.09 (0.30) | −1.45 (0.46)* | −0.75 (0.49) |
ALDH1A1 | ||||
 Staining extent | 0.97 (0.40)* | 0.65 (0.40) | −0.31 (0.71) | 0.18 (0.76) |
 Expression score (extent x intensity) | 1.11 (0.41)* | 0.95 (0.40)b | 0.48 (0.63) | 0.61 (0.74) |