| TIL status |  | PD-L1 status |  | ||
---|---|---|---|---|---|---|
Positive (N = 50) | Negative (N = 8) | p value | Positive (N = 10) | Negative (N = 48) | p value | |
Age | ||||||
  < 50 years | 22 | 6 | 0.103 | 8 | 20 | 0.027a |
 >50 years | 28 | 2 |  | 2 | 28 |  |
Size at surgery | ||||||
  < 2 cm | 19 | 5 | 0.191 | 7 | 17 | 0.043a |
  > 2 cm | 31 | 3 |  | 3 | 31 |  |
Histotype | ||||||
 Ductal | 43 | 7 | 0.909 | 8 | 42 | 0.53 |
 Other | 7 | 1 |  | 2 | 6 |  |
Grade | ||||||
 1 and 2 | 32 | 6 | 0.697 | 3 | 33 | 0.45 |
 3 | 20 | 2 |  | 6 | 15 |  |
Lymph node status | ||||||
 Positive | 32 | 5 | 0.934 | 8 | 29 | 0.241 |
 Negative | 18 | 3 |  | 2 | 19 |  |
Hormone receptor status | ||||||
 Positive | 39 | 7 | 0.599 | 8 | 38 | 0.497 |
 Negative | 10 | 1 |  | 1 | 10 |  |
HER2 status | ||||||
 Positive | 10 | 2 | 0.745 | 2 | 10 | 0.952 |
 Negative | 40 | 6 |  | 8 | 38 |  |
Relapse status | ||||||
 Relapse | 9 | 2 | 0.37 | 11 | 0 | 0.159 |
 No relapse | 23 | 2 |  | 21 | 4 |  |
 N/A | 27 | 4 |  | 16 | 6 |  |
ΔTILs (pre–post) | ||||||
 Positive or zero | 15 | 5 | 0.01 | 19 | 1 | 0.206 |
 Negative | 23 | 0 |  | 19 | 4 |  |