Skip to main content
Fig. 1 | Breast Cancer Research

Fig. 1

From: Effect of neoadjuvant chemotherapy on tumor-infiltrating lymphocytes and PD-L1 expression in breast cancer and its clinical significance

Fig. 1

Stromal tumor-infiltrating lymphocyte (TIL) changes prior to (pre-neoadjuvant) and following (post-neoadjuvant) neoadjuvant chemotherapy. a Changes from diagnostic core biopsy (pre-chemotherapy) to surgical specimen (post-chemotherapy) in all cases. Right: comparison of the two groups by Mann–Whitney test (mean and SEM, p = 0.09). Similar representation of changes before and after chemotherapy in estrogen receptor (ER)-positive cases (b) and ER-negative cases (c). d TIL count in residual tumor specimens in ER-negative and ER-positive cases is significantly different (mean and SEM shown). e Changes from pre-neoadjuvant to post-neoadjuvant (ΔTILs) display no significant difference in ER-positive and ER-negative tumors (mean and SEM, Mann–Whitney test). f Average stromal TIL percentage in residual tumor specimens (post-neoadjuvant) in relation to programmed death ligand 1 (PD-L1) status (Mann–Whitney test)

Back to article page