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Fig. 1 | Breast Cancer Research

Fig. 1

From: Gene expression modules in primary breast cancers as risk factors for organotropic patterns of first metastatic spread: a case control study

Fig. 1

Overview of cases and gene expression datasets. For each metastatic population (Visceral only, Bone + Visceral, and Bone only) 400 cases were sampled, and three possible controls were matched to each case by calendar time of event. A random sample of case-control sets was taken forward to tissue assessment for RNA extraction (Additional file 1: Supplementary methods). Extracted RNA was available for a total of 742 case-control (1:1) pairs, comprising a total of 1277 individual patients. A detailed overview of patients and samples included in the design and in the gene expression datasets is shown in Additional file 2: Figure S1A, B

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