Epithelial requirement for in vitro proliferation and xenograft growth and metastasis of MDA-MB-468 human breast cancer cells: oncogenic rather than tumor-suppressive role of E-cadherin

Table 6 Local lymphovascular invasion

Group	Number of mice inoculated	With tumors	With local invasion	Percentage of invasion
468-shSCR	13	13	8	61.5
468-shCDH1-B	13	13	8	61.5
468-shCDH1-D	12	12	11	91.7
468-pcDNA3	12	9	5	41.7
468-CDH1	12	12	11	91.7

Local invasion of the lymphovascular spaces was a common feature in many tumors across all the groups, and no clear association was detected between it and the E-cadherin status of the primary tumors

ISSN: 1465-542X