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Table 6 Local lymphovascular invasion

From: Epithelial requirement for in vitro proliferation and xenograft growth and metastasis of MDA-MB-468 human breast cancer cells: oncogenic rather than tumor-suppressive role of E-cadherin

Group Number of mice inoculated With tumors With local invasion Percentage of invasion
468-shSCR 13 13 8 61.5
468-shCDH1-B 13 13 8 61.5
468-shCDH1-D 12 12 11 91.7
468-pcDNA3 12 9 5 41.7
468-CDH1 12 12 11 91.7
  1. Local invasion of the lymphovascular spaces was a common feature in many tumors across all the groups, and no clear association was detected between it and the E-cadherin status of the primary tumors