Skip to main content

Table 1 Patient demographics

From: A phase I trial of ganetespib in combination with paclitaxel and trastuzumab in patients with human epidermal growth factor receptor-2 (HER2)-positive metastatic breast cancer

Baseline characteristic

Number

Total enrolled

9

Median (range) age (years) at study enrollment

46 (29–65)

Subtype

 ER+/HER2+

7

 ER–/HER2+

2

Median ECOG performance status

0 (0–1)

Prior lines of chemotherapy in the metastatic setting, median (range)

3 (2–6)

Prior lines of endocrine therapies in the metastatic setting, median (range)

1 (1–3)

Prior number of anti-HER2 agents in the metastatic setting, median (range)a

3 (2–4)

  1. negative, + positive, ECOG Eastern Cooperative Oncology Group, ER estrogen receptor, HER2 human epidermal growth factor receptor 2, T-DM1 ado-trastuzumab emtansine
  2. aIncluding prior pertuzumab in 9/9 patients and T-DM1 in 8/9 patients