Body size in early life and risk of breast cancer

Breast Cancer Research

Table 7 Odds ratios (ORs) and corresponding 95% confidence intervals (CI) for the associations between body size at age 18 years and tumor size in KARMA

Body size at age 18	T0–T1 (n)	T2–T4 (n)	Multivariable OR (95% CI)^a
Subset of women with percent mammographic density <25%
Small	81	43	1.00 (Reference)
Medium	223	61	0.53 (0.33–0.85)
Large	33	6	0.34 (0.13–0.88)
P _trend			0.008
Subset of women with percent mammographic density ≥25%
Small	87	49	1.00 (Reference)
Medium	143	68	0.83 (0.51–1.33)
Large	15	5	0.56 (0.19–1.68)
P _trend			0.249

T tumor size
^aAdjusted for age, age at menarche, number of children, use of hormone replacement therapy and family history of breast cancer

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