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Table 2 Univariate and multivariate analyses of prognostic factors for overall survival, disease-free survival, distant metastasis-free survival, and locoregional recurrence-free survival

From: miR-629-3p may serve as a novel biomarker and potential therapeutic target for lung metastases of triple-negative breast cancer

Variables OS DFS DMFS LRRFS
Univariate Multivariate Univariate Multivariate Univariate Multivariate Univariate Multivariate
P value HR 95% CI P value P value HR 95% CI P value P value HR 95% CI P value P value HR 95% CI P value
Age (years) 0.478     0.384     0.220     0.245    
Menopause 0.594     0.910     0.852     0.994    
T <0.001 1.2 0.9–1.5 0.069 <0.001 1.2   0.041 <0.001 1.2 0.9–1.5 0.095 <0.001 1.3 0.9–1.7 0.053
N <0.001 1.3 1.0–1.6 0.034 <0.001 1.4   0.007 <0.001 1.3 1.1–1.7 0.012 <0.001 1.3 0.9–1.8 0.083
TNM stage <0.001 1.8 1.1–2.9 0.016 <0.001 1.6   0.021 <0.001 1.9 1.2–2.9 0.007 <0.001 1.4 0.8–2.5 0.247
Surgery 0.774     0.985     0.784     0.610    
Chemotherapy 0.167     0.180     0.192     0.057    
Grade 0.016 1.4 1.1–1.8 0.004 0.003 1.4   0.001 0.002 1.5 1.2–1.9 <0.001 0.254    
Ki-67 0.391     0.499     0.523     0.401    
LVI <0.001 2.0 1.4–2.9 <0.001 <0.001 1.4   0.047 <0.001 1.6 1.1–2.3 0.008 0.045 0.9 0.6–1.7 0.971
miR-629-3p <0.001 1.3 0.9–1.8 0.089 0.002 1.1   0.558 <0.001 1.2 0.9–1.7 0.191 0.116    
  1. Abbreviations: DFS Disease-free survival, DMFS Distant metastasis-free survival, LRRFS Locoregional recurrence-free survival, LVI Lymphovascular invasion