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Table 4 Comparison of immune gene expression between high versus low 12-gene chemokine signature scores in breast cancer

From: Evaluation of invasive breast cancer samples using a 12-chemokine gene expression score: correlation with clinical outcomes

Immune genes Mean values CS high Mean values CS low Adjusted p value
BTLA 4.374103903 3.429457529 1.24E-30
BTLA 5.104717271 3.593084013 1.87E-41
CD14 10.54798175 10.07803072 1.00E-05
PD-L1 3.631025974 3.235645445 1.30E-12
PD-L1_2 7.857288587 6.090272006 1.47E-46
PD-L1_3 4.201128981 3.576133806 1.91E-19
CD69 8.500662981 7.112610181 9.03E-20
CTLA4 8.639718923 6.131656168 3.88E-59
CXCL12 5.909474361 5.901681942 1
CXCL12_2 10.2584955 10.211514 1
CXCL12_3 10.37964834 10.27661866 1
FAP 10.84403166 10.76480457 1
Granzyme B 8.749378335 5.759872516 6.87E-58
Granzyme B_2 8.799689613 5.545019987 3.45E-58
TIM3 8.841433445 8.110355729 1.97E-15
IDO1 8.966759748 5.712505632 6.00E-60
Interferon gamma 5.094852239 3.264361445 6.63E-38
IL10 3.717511361 3.298523542 6.72E-10
IL2 2.964185658 2.676063232 1.25E-10
IL4 2.703027632 2.795378406 0.215457875
IL6 6.746965877 5.733926619 7.80E-08
JAK1 5.3000556 5.132389587 0.094531305
JAK1_2 9.330956665 9.094484413 0.024599705
JAK1_3 8.237782039 7.989419813 0.019509776
JAK1_4 10.80787464 10.7258152 1
LAG3 6.455917471 4.991195632 1.00E-43
LEM 3.0760666 3.059619619 1
LEM_2 6.110419432 6.080285335 1
LEM_3 9.176335942 9.183974716 1
LEM_4 9.772502419 9.798403587 1
MICA 8.81120191 8.799736368 1
MICA_2 4.690884181 4.882048935 1
MICA_3 4.891286084 5.075915484 1
MICA_4 8.791930277 8.781289103 1
MICA_5 4.693718703 4.827482226 1
MICA_6 9.571045 9.576738355 1
MICA_7 9.358850632 8.743868929 4.28E-07
CD56 5.580049794 5.914039671 1
CD56_2 4.629692439 4.864664335 1
CD56_3 3.710274097 3.817752942 0.453890338
CD56_4 5.035893445 5.352795768 1
CD56_5 5.70368229 6.044969677 1
NFKB 9.915169981 9.803810142 0.846175728
NOS1 2.902139606 2.921106129 1
NOS1_2 2.673781071 2.701705103 1
NOS1_3 2.993182194 2.955307058 1
PD-1 4.767050374 4.533298226 6.38E-07
CD31 8.753703548 8.316285368 4.15E-05
CD31_2 9.199703387 8.773391155 2.09E-06
CD31_3 11.64218184 11.36531043 0.001319025
CD31_4 9.182763284 8.7672612 1.42E-05
PRF1 9.356943658 7.50412171 3.40E-47
STAT1 11.75385782 10.98503868 1.18E-40
STAT1_2 10.51426123 8.908289794 6.77E-47
STAT1_3 4.153055619 4.103139297 1
STAT1_4 8.731805852 8.584214968 0.320434448
STAT1_5 10.17262105 10.11776818 1
LIGHT 5.336076219 4.766262271 7.19E-20
VEGA 8.954027852 8.900788865 1
VEGA_2 10.5322381 10.51156299 1
VEGA_3 9.817599665 9.782464335 1
  1. Bolded gene probes are those with false discovery rate of <1% across all representative probes for a particular gene