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Table 1 Sensitivity and specificity for detecting BRCA1-like status samples using BRCA1ness

From: The BRCA1ness signature is associated significantly with response to PARP inhibitor treatment versus control in the I-SPY 2 randomized neoadjuvant setting

 

MLPA BRCA1-like

MLPA non-BRCA1-like

BRCA1ness positive

59

18

BRCA1ness negative

2

49

 

Sensitivity

Specificity

96.7%

73.1%

  1. MLPA multiplex ligation-dependent probe amplification
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Breast Cancer Research

ISSN: 1465-542X

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