Skip to main content

Table 1 Characteristics of human subjects

From: MicroRNA-200c and microRNA- 141 are regulated by a FOXP3-KAT2B axis and associated with tumor metastasis in breast cancer

  First cohort Second cohort
Categories BCa Benignb Familyc Controld BCa Controld
Total number 39 30 21 44 75 50
Recruiting time, years 2004–2014 2004–2014 2004–2014 2004–2014 2004–2014 2004–2014
Median age (range), years 51 (30–73) 51 (40–63) 47 (33–71) 50 (36–70) 52 (32–75) 52 (37–71)
Race
 Caucasian 26 28 20 36 75 50
 African-American 11 1 1 7 0 0
 Other 2 1 0 1 0 0
ER status
 Positive 26     46  
 Negative 4     29
 Unknown 9     0
PR status
 Positive 24     41  
 Negative 5     34
 Unknown 10     0
HER2 status
 Positive 6     28  
 Negative 25     47
 Unknown 8     0
 Histological subtype
 Ductal 30     58  
 Lobular 2     9
 Both 2     0
 Unclassified 5     8
Tumor grade
 Well 2     4  
 Moderate 13     38
 Poor 17     33
 Unknown 7     0
Tumor stage
 Localized       
 DCIS (pTis) 6     0
 Early (pT1-2N0M0) 15     42
 Advanced (pT3-4N0M0) 4     8
Metastatic
 Regional (pT1-4 N1-3 M0) 11     15  
 Distant (pT1-4 M1) 3     10
  1. ER estrogen receptor, PR progesterone receptor, HER2 human epidermal growth factor receptor, DCIS ductal carcinoma in situ, T tumor, N node, M metastasis. aPatients with breast cancer. bPatients with benign breast tumor. cNormal healthy women with family history of breast cancer. dNormal healthy women without family history of breast cancer