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Table 1 Characteristics of human subjects

From: MicroRNA-200c and microRNA- 141 are regulated by a FOXP3-KAT2B axis and associated with tumor metastasis in breast cancer

 

First cohort

Second cohort

Categories

BCa

Benignb

Familyc

Controld

BCa

Controld

Total number

39

30

21

44

75

50

Recruiting time, years

2004–2014

2004–2014

2004–2014

2004–2014

2004–2014

2004–2014

Median age (range), years

51 (30–73)

51 (40–63)

47 (33–71)

50 (36–70)

52 (32–75)

52 (37–71)

Race

 Caucasian

26

28

20

36

75

50

 African-American

11

1

1

7

0

0

 Other

2

1

0

1

0

0

ER status

 Positive

26

   

46

 

 Negative

4

   

29

 Unknown

9

   

0

PR status

 Positive

24

   

41

 

 Negative

5

   

34

 Unknown

10

   

0

HER2 status

 Positive

6

   

28

 

 Negative

25

   

47

 Unknown

8

   

0

 Histological subtype

 Ductal

30

   

58

 

 Lobular

2

   

9

 Both

2

   

0

 Unclassified

5

   

8

Tumor grade

 Well

2

   

4

 

 Moderate

13

   

38

 Poor

17

   

33

 Unknown

7

   

0

Tumor stage

 Localized

      

 DCIS (pTis)

6

   

0

 Early (pT1-2N0M0)

15

   

42

 Advanced (pT3-4N0M0)

4

   

8

Metastatic

 Regional (pT1-4 N1-3 M0)

11

   

15

 

 Distant (pT1-4 M1)

3

   

10

  1. ER estrogen receptor, PR progesterone receptor, HER2 human epidermal growth factor receptor, DCIS ductal carcinoma in situ, T tumor, N node, M metastasis. aPatients with breast cancer. bPatients with benign breast tumor. cNormal healthy women with family history of breast cancer. dNormal healthy women without family history of breast cancer
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Breast Cancer Research

ISSN: 1465-542X

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