From: BRCA promoter methylation in sporadic versus BRCA germline mutation-related breast cancers
Probe | BRCA1, total n = 5 (%) | BRCA2, total n = 4 (%) | Total, n = 9 (%) | Cutoffa |
---|---|---|---|---|
BRCA1.1 | 0 (0) | 0 (0) | 0 (0) | >15% |
BRCA1.2 | 2 (40) | 1 (25) | 3 (30) | >17% |
BRCA1.3 | 1 (20) | 0 (0) | 1 (11.1) | >15% |
BRCA1 totalb | 2 (40) | 1 (25) | 3 (30) | Â |
BRCA2.1 | 2 (40) | 2 (50) | 4 (44.4) | >19% |
BRCA2.2 | 1 (20) | 0 (0) | 1 (11.1) | >15% |
BRCA2.3 | 2 (50) | 0 (0) | 2 (22.2) | >15% |
BRCA2.4 | 0 (0) | 0 (0) | 0 (0) | >15% |
BRCA2 totalb | 3 (60) | 2 (50) | 5 (55.5) | Â |