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Table 2 Observed and predicted (PREDICT v2) deaths, by cause of death and data set

From: An updated PREDICT breast cancer prognostication and treatment benefit prediction model with independent validation

Study Number Observed Predicted Difference (%) P value
Total mortality
 ECRIC 5738 1550 1600 3 0.21
 BCOS 981 255 270 6 0.34
 NTBCS 1944 488 468 −4 0.36
 POSH 2609 544 621 12 0.00
 Total 11,272 2837 2958 4 0.023
Breast cancer-specific mortality
 ECRIC 5738 932 953 2 0.48
 BCOS 981 227 244 7 0.25
 NTBCS 1944 325 331 2 0.74
 POSH 2609 527 581 9 0.018
 Total 11,272 2011 2110 5 0.027
Non-breast cancer mortality
 ECRIC 5738 618 646 4 0.25
 BCOS 981 28 26 −9 0.66
 NTBCS 1944 163 137 −19 0.039
 POSH 2609 17 39 57 <0.001
 Total 11,272 826 848 3 0.44
  1. Abbreviations: BCOS Breast Cancer Outcome Study of Mutation Carriers, ECRIC Eastern Cancer Registration and Information Centre, NTBCS Nottingham/Tenovus Breast Cancer Study, POSH Prospective study of Outcomes in Sporadic and Hereditary breast cancer