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Table 1 Characteristics of participating girls, by pubertal outcomes; the LEGACY Girls Study

From: Pubertal development in girls by breast cancer family history: the LEGACY girls cohort

Category Entire cohort (n = 1040) Breast Tanner, girls aged <13 (n = 801) Pubic hair Tanner, girls aged <13 (n = 835) Menarche, girls ≥10 (n = 506)
Stage T1
(n = 506)
Stage T2+
(n = 295)
Stage T1
(n = 556)
Stage T2+
(n = 279)
No menses
(n = 313)
Menses
(n = 193)
Continuous variables, mean (SD)
 Age (years) 10.1 (2.4) 8.7 (1.7) 11.2 (1.3) 8.7 (1.7) 11.2 (1.4) 11.4 (1.0) 13.2 (1.2)
 Weight (kg) 37.8 (14.6) 29.6 (8.4) 46.0 (12.4) 30.1 (9.4) 44.7 (13.2) 41.1 (10.8) 55.5 (13.1)
 Height (cm) 142.6 (15.3) 133.5 (11.0) 151.8 (10.7) 133.4 (11.1) 151.2 (11.1) 149.9 (9.2) 161.2 (7.5)
 BMI (kg/m2) 18.0 (4.3) 16.4 (3.4) 19.8 (4.3) 16.7 (3.7) 19.3 (4.3) 18.2 (3.8) 21.3 (4.3)
 Maternal age at menarche 12.7 (1.5) 12.9 (1.5) 12.4 (1.5) 12.8 (1.5) 12.6 (1.5) 12.9 (1.5) 12.4 (1.5)
 Maternal age at daughter’s birth 32.3 (5.5) 32.6 (5.4) 31.8 (5.7) 32.5 (5.4) 32.0 (5.7) 32.4 (5.2) 31.2 (5.8)
Categorical variables, count (%)
 Overweight
   ≥ 85th percentile 193 (18.6) 60 (11.9) 90 (30.5) 81 (14.6) 71 (25.5) 46 (14.7) 55 (28.5)
 Race/ethnicity
  Hispanic 193 (18.6) 79 (15.6) 60 (20.3) 88 (15.8) 60 (21.5) 44 (14.1) 58 (30.1)
  Black 78 (7.5) 27 (5.3) 34 (11.5) 27 (4.9) 36 (12.9) 22 (7.0) 17 (8.8)
  Non-hispanic white 646 (62.1) 343 (67.8) 172 (58.3) 371 (66.7) 160 (57.4) 209 (66.8) 91 (47.2)
  Asian 93 (8.9) 46 (9.1) 19 (6.4) 55 (9.9) 16 (5.7) 31 (9.9) 19 (9.4)
  Mixed race/ethnicity 30 (2.9) 11 (2.2) 10 (3.4) 15 (2.7) 7 (2.5) 7 (2.2) 8 (4.2)
 Study site  
  Philadelphia 154 (14.8) 72 (14.2) 53 (18.0) 74 (13.3) 52 (18.6) 63 (20.1) 25 (13.0)
  Utah 164 (15.8) 86 (17.0) 32 (10.9) 100 (18.0) 30 (10.8) 45 (14.4) 16 (8.3)
  New York 168 (16.2) 95 (18.8) 45 (15.2) 102 (18.4) 38 (13.6) 39 (12.5) 28 (14.5)
  Ontario, Canada 192 (18.5) 103 (20.4) 53 (18.0) 113 (20.3) 49 (17.6) 53 (16.9) 37 (19.2)
  San Francisco Bay Area 362 (34.8) 150 (29.6) 112 (38.0) 167 (30.0) 110 (39.4) 113 (36.1) 87 (45.1)
 Maternal education
  Some college/vocational/technical school or less 284 (27.3) 114 (22.5) 101 (35.1) 139 (25.0) 85 (30.5) 77 (24.6) 73 (37.8)
  Bachelor’s degree 377 (36.3) 194 (38.3) 85 (29.5) 210 (37.8) 90 (32.3) 107 (34.2) 62 (32.1)
  Graduate degree 353 (33.9) 191 (37.8) 102 (35.4) 199 (35.8) 98 (35.1) 124 (39.6) 45 (23.3)
 Breast cancer family history (BCFH)
  No BCFH 497 (47.8) 267 (52.7) 142 (48.1) 277 (49.8) 146 (52.3) 154 (49.2) 84 (43.5)
  Any BCFH 533 (51.3) 239 (47.2) 153 (51.9) 279 (50.2) 133 (47.7) 159 (50.8) 109 (56.5)
  First-degree BCFH 219 (21.1) 89 (17.6) 64 (21.7) 99 (17.8) 63 (22.6) 71 (22.7) 53 (27.5)
  Second-degree BCFH Only 313 (30.1) 150 (29.6) 89 (30.2) 180 (32.4) 70 (25.1) 88 (28.1) 56 (29.0)
  1. BMI body mass index, SD standard deviation.