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Fig. 3 | Breast Cancer Research

Fig. 3

From: Rapid evaporative ionisation mass spectrometry of electrosurgical vapours for the identification of breast pathology: towards an intelligent knife for breast cancer surgery

Fig. 3

Multivariate statistical analysis of the combined cut and coag model. a Unsupervised principal component (PC) analysis of the spectral differences (600–1000 m/z) between normal tissue compared to breast cancer in the cut and coag electrosurgical modalities. b Supervised linear discriminant analysis plot comparing normal tissue (N) to tumour/cancer (T) regardless of electrosurgical modality. c Flow diagram of sample selection for building of the rapid evaporative ionisation mass spectrometry (REIMS) database. d Confusion matrix demonstrating diagnostic accuracy of the combined electrosurgical model following leave-one-patient-out cross-validation (LV1), with sensitivity (93.4%) and specificity (94.9%)

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