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Table 1 Participant characteristics and use of non-steroidal anti-inflammatory medications, California Teachers Study, 2005–2012

From: Regular and low-dose aspirin, other non-steroidal anti-inflammatory medications and prospective risk of HER2-defined breast cancer: the California Teachers Study

Characteristic Number Percentage
Age (years)a
 <40 1781 3.1
 40–49 7020 12.3
 50–59 16,651 29.1
 60–69 15,779 27.6
 70–79 10,482 18.3
 80–89 4812 8.4
  ≥ 90 639 1.1
Raceb
 White 50,250 87.9
 Hispanic 2220 3.9
 Asian/Pacific Islander 2135 3.7
 Black 1183 2.1
 Other/mixed 972 1.7
 Missing 404 0.7
Age at menarche (years)b
 <12 12,799 22.4
  ≥ 12 43,635 76.3
 Missing 730 1.3
Age at first full-term pregnancy (years)b
 Nulliparous 14,157 24.8
  < 25 15,171 26.5
  ≥ 25 26,909 47.1
 Missing 927 1.6
Total time breastfeeding (months)b
 Never or <12 40,567 71.0
  ≥ 12 15,446 27.0
 Missing 1,151 2.0
History of a benign breast biopsyb
 No 47,812 83.6
 Yes 9175 16.1
 Missing 177 0.3
Family history of breast cancer (mother or sister)b
 No 48,736 85.3
 Yes 6763 11.8
 Missing data or participant was adopted 1665 2.9
History of hospitalization for myocardial infarctionc
 No 56,586 99.0
 Yes 578 1.0
History of diabetes mellitusa
 No 54,433 95.2
 Yes 2715 4.8
 Missing 16 0.0
Strenuous plus moderate physical activity in the past 3 years (hours per week)a
 <3 26,079 45.6
 ≥3 30,909 54.1
 Missing 176 0.3
Alcohol consumption (grams per day)a
 None or <20 46,033 80.5
 ≥20 8652 15.1
 Missing 2479 4.3
Body mass index (kg/m2)a
 <25.0 29,509 51.6
 25.0–29.9 16,619 29.1
 ≥30.0 10,359 18.1
 Missing 677 1.2
Menopausal status and hormone therapy (HT) usea
 Premenopausal 6314 11.1
 Perimenopausal or postmenopausal   
  No HT in the last 5 years 27,397 47.9
  Used HT in the last 5 years, but not currently using 10,142 17.7
  Current HT use 11,420 20.0
 Unknown menopausal status or HT use 1891 3.3
Regular-dose aspirin use at baselineb
 No NSAID used 37,075 64.9
 No regular-dose aspirin use, but used ibuprofen 7002 12.3
 Used 1–3 days/week 6340 11.1
 Used 4+ days/week 5732 10.0
 Unknown 1015 1.8
Low-dose aspirin use at the 10-year follow upa
 Never in the past 3 years
  No NSAID use in the past 3 yearse 21,421 37.5
  No low-dose aspirin use, use of 1+ type(s) 15,678 27.4
  No low-dose aspirin use, unknown use of 1+ type(s) 1829 3.2
 Former 2766 4.8
 Current, 1–2 tablets/week 915 1.6
 Current, 3–4 tablets/week 1163 2.0
 Current, 5–6 tablets/week 1406 2.5
 Current, 7+ tablets/week 10,421 18.2
 Unknown 1565 2.7
Regular-dose aspirin use at the 10-year follow upa
 Never in the past 3 years
  No NSAID use in the past 3 yearse 21,421 37.5
  No regular-dose aspirin use, use of 1+ type(s) 23,451 41.0
  No regular-dose aspirin use, unknown use for 1+ type(s) 2253 3.9
 Former/irregular 2378 4.2
 Current, 3+ tablets/week 6387 11.2
 Unknown 1274 2.2
Ibuprofen use at the 10-year follow upa
 Never in the past 3 years
  No NSAID use in the past 3 yearse 21,421 37.5
  No ibuprofen use, use of 1+ type(s) 18,219 31.9
  No ibuprofen use, unknown use for 1+ type(s) 1499 2.6
 Former/irregular 3679 6.4
 Current, 3+ tablets/week 10,382 18.2
 Unknown 1964 3.4
Other non-steroidal use at the 10-year follow upa
 Never in the past 3 years
  No NSAID use in the past 3 yearse 21,421 37.5
  No other non-steroidal use, use of 1+ type(s) 25,529 44.7
  No other non-steroidal use, unknown use for 1+ type(s) 2307 4.0
 Former/irregular 2301 4.0
 Current, 3+ tablets/week 4263 7.5
 Unknown 1343 2.4
Cox-2 inhibitor use at the 10-year follow upa
 Never in the past 3 yearse
  No NSAID use in the past 3 yearse 21,421 37.5
  No Cox-2 inhibitor use, use of 1+ type(s) 28,055 49.1
  No Cox-2 inhibitor use, unknown use for 1+ type(s) 2625 4.6
 Former/irregular 2807 4.9
 Current, 3+ tablets/week 1064 1.9
 Unknown 1192 2.1
  1. aFrom the 10-year follow-up questionnaire completed in 2005–2006. bFrom the baseline questionnaire completed in 1995–1996. cFrom linkage with the Office of Statewide Health Planning and Development (OSHPD) hospital discharge database from 1991 until the 10-year follow-up questionnaire. dIncluded aspirin and ibuprofen used regularly (at least once a week) reported on the baseline questionnaire. eIncluded aspirin, low-dose aspirin, ibuprofen, Cox-2 inhibitors, and other NSAIDs currently used regularly (at least once a week) reported on the 10-year follow-up questionnaire. NSAID non-steroidal anti-inflammatory drug