Fig. 3
From: TIMELESS contributes to the progression of breast cancer through activation of MYC
TIM enhances the tumorigenicity of breast cancer cells in vivo. a Soft agar growth analysis of indicated cells with TIM overexpression or knockdown (left panel) and quantification of colony number (right panel). *P < 0.05. b-d In vivo tumorigenesis assay of MCF-7 cells with TIM overexpression or knockdown. Representative images of the tumors in each group b. Growth curves (c) and tumor weight (d) for tumor formation when different numbers of the indicated cells were injected. Mean tumor volumes are plotted. e Immunohistochemistry staining of the xenograft tumor by anti-TIM antibody. Representative photographs are shown