Table 2 Odds ratio (95% CI) of developing breast cancer by category and 5% increase of EZH2 expression in epithelium or stroma in normal breast tissue

 Number of subjects (cases/controls)

48/184

10/55

16/30

74/269

  Model 1^a

Ref.

0.70 (0.32–1.54)

2.44 (1.15–5.17)

0.078

1.17 (1.03–1.34)

0.021

  Model 2^b

Ref.

0.73 (0.3–1.63)

2.67 (1.24–5.76)

0.053

1.20 (1.04– 1.38)

0.010

  Model 3^c

Ref.

0.79 (0.32–1.96)

2.95 (1.1–7.84)

0.092

1.22 (1.02–1.46)

0.026

 Number of subjects (cases/controls)

53/208

20/72

5/12

78/292

  Model 1^a

Ref.

1.06 (0.58–1.96)

1.94 (0.62–6.07)

0.379

1.12 (0.93–1.35)

0.230

  Model 2^b

Ref.

1.20 (0.6 –2.23)

2.13 (0.67–6.80)

0.227

1.15 (0.95–1.39)

0.147

  Model 3^c

Ref.

1.32 (0.61–2.85)

2.45 (0.64–9.37)

0.189

1.18 (0.94–1.49)

0.157