Skip to main content

Table 2 ZOL-induced modifications to peripheral blood cell counts over time

From: Zoledronic acid alters hematopoiesis and generates breast tumor-suppressive bone marrow cells

  

Control

Three days post ZOL

Five days post ZOL

Ten days post ZOL

Nude

Monocytes

0.37 ± 0.10

0.21 ± 0.09

0.27 ± 0.11

0.45 ± 0.11

Neutrophils

2.78 ± 0.46

1.73 ± 0.48

1.86 ± 0.18

2.28 ± 0.65

C57BL/6

Monocytes

0.82 ± 0.20

0.28 ± 0.12*

0.14 ± 0.04*

0.62 ± 0.14

Neutrophils

1.56 ± 0.16

0.98 ± 0.16*

0.79 ± 0.33*

1.41 ± 0.29

Platelets

438.6 ± 32.10

477.0 ± 87.66

653.3 ± 68.50*

512.2 ± 64.50

  1. Average numbers of indicated peripheral blood cells (K/μL ± SEM) from nude and C57BL/6 mice as determined by HEMAVET® at the indicated time points after control treatment or one 100-μg/kg dose of zoledronic acid (ZOL); n = 4–5 mice per group; *p ≤ 0.05
Back to article page

Breast Cancer Research

ISSN: 1465-542X

Contact us