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Fig. 1 | Breast Cancer Research

Fig. 1

From: Immune profiles of elderly breast cancer patients are altered by chemotherapy and relate to clinical frailty

Fig. 1

Estimated mean immune biomarker levels (with 95% confidence intervals) in patients undergoing chemotherapy (green lines) or not having chemotherapy (blue lines) at baseline, 3 months and 12 months after starting therapy. Relative to patients not receiving chemotherapy (control group (CG)), those receiving chemotherapy (chemotherapy group (CTG)) had a lower ratio of CD4:CD8 T cells at 3 months before partial normalization (a), while there were relative increases in CTG patients at 3 months followed by normalization at 12 months in CD8 + CD27-CD28– (b) CD4+ T effector memory re-expressing CD45RA (TEMRA) memory cells (c) and CD15+ granulocytic cells (d). There were relative decreases in CD8+ central memory cells (e) and CD8+ CD27+ CD28+ T cells (f) in the CTG at 3 months before normalization. Chemo chemotherapy group

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