Table 1 Analysis of PIK3CA mutations per exon and treatment group
| Â | Group A | Group B | Group C | Group D | Overall (pooled groups) | |||||
|---|---|---|---|---|---|---|---|---|---|---|
Exon n (Mut/total) | pCR, n (%) | non-pCR, n (%) | pCR, n (%) | non-pCR, n (%) | pCR, n (%) | non-pCR, n (%) | pCR, n (%) | non-pCR, n (%) | pCR, n (%) | non-pCR, n (%) |
Exon 7 | n = 2 | n = 1 | n = 1 | n = 0 | n = 4 | |||||
(4/290) | 0 | 2 (100) | 0 | 1 (100) | 0 | 1 (100) | 0 | 0 | 0 | 4 (100) |
Exon 9 | n = 8 | n = 5 | n = 5 | n = 10 | n = 28 | |||||
(28/328) | 0 | 8 (100) | 1 (20.0) | 4 (80.0) | 0 | 5 (100) | 1 (10.0) | 9 (90.0) | 2 (7.1) | 26 (92.9) |
Exon 20 | n = 20 | n = 15 | n = 17 | n = 14 | n = 66 | |||||
(66/338) | 7 (35.0) | 13 (65.0) | 7 (46.7) | 8 (53.3) | 2 (11.8) | 15 (88.2) | 3 (21.4) | 11 (78.6) | 19 (28.8) | 47 (71.2) |