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Table 1 Distribution of CD68-positive macrophage cells and CLS in postmenopausal women diagnosed with invasive breast cancer (n = 83)

From: Relationship between crown-like structures and sex-steroid hormones in breast adipose tissue and serum among postmenopausal breast cancer patients

  n (%) No. of CD68-positive cells p value No. of CD68-positive cells per 100 mm2 fat area p value
Overall 83 (100) 150.0 (5–1237)   13 (1–737)  
 CLS-positive 30 (36) 250.5 (34–1237) <0.001 20 (2–406) 0.23
 CLS-negative 53 (64) 113.0 (5–522)   10 (1–737)  
ER-positive
 CLS-positive 21 (35) 253.0 (34–1237) <0.001 19 (3–140) 0.69
 CLS-negative 39 (65) 109.0 (5–481)   12 (2–364)  
ER-negative
 CLS-positive 9 (39) 188.0 (106–588) 0.06 39 (2–406) 0.16
 CLS-negative 14 (61) 123.5 (6–522)   10 (1–737)  
  1. Values are shown as median (range) unless otherwise indicated
  2. p values (Mann Whitney U test) are shown for comparison of CLS-positive versus CLS-negative
  3. CLS crown-like structures, ER estrogen receptor