TY - JOUR AU - Mullooly, Maeve AU - Yang, Hannah P. AU - Falk, Roni T. AU - Nyante, Sarah J. AU - Cora, Renata AU - Pfeiffer, Ruth M. AU - Radisky, Derek C. AU - Visscher, Daniel W. AU - Hartmann, Lynn C. AU - Carter, Jodi M. AU - Degnim, Amy C. AU - Stanczyk, Frank Z. AU - Figueroa, Jonine D. AU - Garcia-Closas, Montserrat AU - Lissowska, Jolanta AU - Troester, Melissa A. AU - Hewitt, Stephen M. AU - Brinton, Louise A. AU - Sherman, Mark E. AU - Gierach, Gretchen L. PY - 2017 DA - 2017/01/19 TI - Relationship between crown-like structures and sex-steroid hormones in breast adipose tissue and serum among postmenopausal breast cancer patients JO - Breast Cancer Research SP - 8 VL - 19 IS - 1 AB - Postmenopausal obesity is associated with increased circulating levels of androgens and estrogens and elevated breast cancer risk. Crown-like structures (CLS; microscopic foci of dying adipocytes surrounded by macrophages) are proposed to represent sites of increased aromatization of androgens to estrogens. Accordingly, we examined relationships between CLS and sex-steroid hormones in breast adipose tissue and serum from postmenopausal breast cancer patients. SN - 1465-542X UR - https://doi.org/10.1186/s13058-016-0791-4 DO - 10.1186/s13058-016-0791-4 ID - Mullooly2017 ER -