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Table 3 Frequency of PIK3CA mutations in classic lobular carcinoma in situ (LCIS)/invasive lobular cancer (ILC)

From: PIK3CA mutations are common in lobular carcinoma in situ, but are not a biomarker of progression

Mutation (total number of cases) Pure LCIS (27) inv-LCIS (28) ILC (25)
PIK3CA_pH1047R_c3140A_G 3 (1558,1717, 04078a) 3 (1731, 1965, 1604) 2a (1731,1604)
1965- no tissue left
PIK3CA_pH1047R_c3140A_T 0 0 0
PIK3CA_pE542K_c1624G_A 1 (1339) 3 (1063,1604, 1640) 3 (1063, 1604, 1640)
PIK3CA_pE545K_c1636C_A 0 0 0
PIK3CA_pE545K_c1633G_A 1 (1078) 2 (1270, 1604) 2 (1270,1126)
Total number of cases with PIK3CA Mutations 5 6 6
  1. asample IDs (italics represent samples with multiple PIK3CA mutations)