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Table 3 Frequency of PIK3CA mutations in classic lobular carcinoma in situ (LCIS)/invasive lobular cancer (ILC)

From: PIK3CA mutations are common in lobular carcinoma in situ, but are not a biomarker of progression

Mutation (total number of cases)

Pure LCIS (27)

inv-LCIS (28)

ILC (25)

PIK3CA_pH1047R_c3140A_G

3 (1558,1717, 04078a)

3 (1731, 1965, 1604)

2a (1731,1604)

1965- no tissue left

PIK3CA_pH1047R_c3140A_T

0

0

0

PIK3CA_pE542K_c1624G_A

1 (1339)

3 (1063,1604, 1640)

3 (1063, 1604, 1640)

PIK3CA_pE545K_c1636C_A

0

0

0

PIK3CA_pE545K_c1633G_A

1 (1078)

2 (1270, 1604)

2 (1270,1126)

Total number of cases with PIK3CA Mutations

5

6

6

  1. asample IDs (italics represent samples with multiple PIK3CA mutations)