Skip to main content

Table 2 Whole exome sequencing of four invasive lobular cancer (ILC) samples and four lobular carcinoma in situ (LCIS) samples (one paired): mutations occurring in two or more samples

From: PIK3CA mutations are common in lobular carcinoma in situ, but are not a biomarker of progression

Gene

Chrom

Number of ILC

samples with

mutation

Number of LCIS

samples with

mutation

Total

HSPG2

1

1

1

2

ROR1

1

1

1

2

SMG7

1

1

1

2

TSSC1

2

2

0

2

PIK3CA

3

3

3

6

DOCK2

5

1

1

2

HAND1

5

2

0

2

UTP23

8

2

0

2

CACNB2

10

1

1

2

COX15

10

1

1

2

OR56B1

11

1

1

2

DDX11

12

1

1

2

PROSER1

13

1

1

2

TPTE2

13

1

1

2

PAK6

15

2

0

2

CDH1

16

3

3

6

PTRF

17

1

1

2

ATP11C

X

1

1

2

ATRX

X

1

1

2