Fig. 2From: PIK3CA mutations are common in lobular carcinoma in situ, but are not a biomarker of progression a Minimal region of gain/amplification on 11q; b correlation of copy number change at 11q13 with fluorescence in situ hybridization (FISH) using the probe for CCND1 and Cyclin D1 immunohistochemical analysis (IHC); c frequency of Cyclin D1 expression as measured by IHC in the discovery set. (SNP = single nucleotide polymorphism, LCIS = lobular carcinoma in situ, Inv LCIS = lobular carcinoma in situ associated with invasive lobular cancer)Back to article page