Table 4 Mean differences in MD measures between processed images and the corresponding raw digital image, by reader and mammography system

Hologic

234

104

0.91

(0.74, 1.08)

1.17

(0.96, 1.39)

0.01

(−0.03, 0.05)

GE

232

98

0.62

(0.44, 0.80)

0.79

(0.57, 1.00)

0.09

(0.07, 0.11)

Fuji

60

15

0.40

(0.20, 0.61)

0.51

(0.26, 0.75)

−0.12

(−0.17, −0.08)

All

526

217

0.72

(0.61, 0.84)

0.93

(0.79, 1.06)

0.03

(−0.08, 0.84)

p for heterogeneity^b

0.007

0.003

<0.001

Hologic

246

109

−0.47

(−0.64, −0.30)

−0.60

(−0.85, −0.34)

0.05

(0.01, 0.09)

GE

218

95

0.05

(−0.12, 0.23)

0.07

(−0.15, 0.30)

0.11

(0.07, 0.16)

Fuji

60

15

−0.76

(−1.03, −0.48)

−0.92

(−1.27, −0.57)

0.06

(−0.01, 0.12)

All

524

219

−0.28

(−0.40, −0.17)

−0.36

(−0.52, −0.19)

0.08

(0.05, 0.11)

p for heterogeneity^b

<0.001

<0.001

0.09

Hologic

232

98

0.10

(−0.04, 0.24)

0.12

(−0.07, 0.31)

0.01

(−0.03, 0.04)

GE

222

95

0.69

(0.52, 0.85)

0.88

(0.64, 1.12)

0.00

(−0.03, 0.04)

Fuji

460

200

0.10

(−0.02, 0.23)

0.13

(−0.03, 0.29)

0.03

(−0.01, 0.08)

All

914

392

0.24

(0.16, 0.33)

0.31

(0.20, 0.43)

0.02

(0.00, 0.04)

p for heterogeneity^b

<0.001

<0.001

0.48

Hologic

834

417

0.55

(0.44, 0.65)

0.74

(0.60, 0.89)

−0.09

(−0.10, −0.08)

GE

360

180

0.43

(0.28, 0.58)

0.50

(0.34, 0.67)

0.08

(0.01, 0.16)

All

1194

597

0.51

(0.43, 0.60)

0.67

(0.56, 0.78)

−0.04

(−0.07, −0.02)

p for heterogeneity^b

0.21

0.056

<0.001

Hologic

1546

679

0.37

(0.29, 0.45)

0.50

(0.39, 0.61)

−0.04

(−0.05, −0.03)

GE

1032

418

0.45

(0.34, 0.56)

0.56

(0.42, 0.69)

0.07

(0.04, 0.10)

Fuji

580

200

0.04

(−0.09, 0.18)

0.06

(−0.10, 0.23)

0.02

(−0.03, 0.07)

All

3158

1297

0.34

(0.28, 0.40)

0.44

(0.36, 0.52)

0.01

(−0.01, 0.02)

p for heterogeneity^b

<0.001

<0.001

<0.001