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Table 2 Proportion of breast cancer cases followed versus the proportion of the general population at highest risk

From: Prediction of breast cancer risk based on common genetic variants in women of East Asian ancestry

PNF (%) PCF (%)
  PRS, SD = 0.38a PRS, SD = 0.55b
1 2.6 3.8
5 10.3 13.7
10 18.4 23.2
20 32.2 38.5
30 44.3 51.0
40 55.0 61.7
50 64.8 70.9
60 73.7 78.9
70 81.7 85.9
80 88.9 91.8
90 95.2 96.6
95 97.9 98.6
99 99.7 99.8
  1. aObserved SD of the PRS distribution in East Asian women
  2. bAssumed SD of the PRS distribution, which corresponds to 30% of the heritability of breast cancer
  3. PCF proportion of cases followed, PNF proportion needed to follow-up, PRS polygenic risk score, SD standard deviation