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Table 1 Characteristics between patients who did or did not experience recurrences

From: High mammographic breast density predicts locoregional recurrence after modified radical mastectomy for invasive breast cancer: a case-control study

  Control group Case group  
n = 121 Percentage n = 121 Percentage P value
Age (years)      
 mean (range) 51.4 (28–89) 51.6 (27–94) 0.738*
 <40 15 12.4 19 15.7 0.725
 40–59 87 71.9 82 67.8  
 >60 19 15.7 20 16.5  
AJCC stage (pathological)      
 I 24 19.8 24 19.8 1.000
 IIA 33 27.3 33 27.3  
 IIB 18 14.9 18 14.9  
 IIIA 20 16.5 20 16.5  
 IIIB 2 1.7 2 1.7  
 IIIC 24 19.8 24 19.8  
Tumor size (mm)      
 0–10 19 15.7 19 15.7 0.911
 10 − 19 19 15.7 22 18.2  
 20 − 50 68 56.2 63 52.1  
 >50 15 12.4 17 14.0  
Positive axillary nodes      
 None 47 38.8 49 40.5 0.956
 1–3 32 26.4 32 26.4  
 >4 42 34.7 40 33.1  
Margin      
 Negative 112 92.6 106 87.6 0.197
 Positive 9 7.4 15 12.4  
Estrogen/progesterone receptor status      
 Negative 46 38.0 44 36.4 0.790
 Positive 75 62.0 77 63.6  
Her2 statusa      
 Negative 92 76.0 88 72.7 0.556
 Positive 29 24.0 33 27.3  
Triple-negative cancer      
 Negative 100 82.6 95 78.5 0.417
 Positive 21 17.4 26 21.5  
MBD quartiles      
 1 (0–25%) 29 24.0 10 8.3 0.023
 2 (25–50%) 53 43.8 59 48.8  
 3 (50–75%) 32 26.4 41 33.9  
 4 (75–100%) 7 5.8 11 9.1  
Adjuvant chemotherapy      
 No 26 21.5 21 17.4 0.417
 Yes 95 78.5 100 82.6  
Adjuvant hormone therapy      
 No 47 38.8 50 41.3 0.694
 Yes 74 61.2 71 58.7  
Adjuvant target therapy      
 No 100 82.6 102 84.3 0.729
 Yes 21 17.4 19 15.7  
Adjuvant radiotherapy      
 No 59 48.8 64 52.9 0.520
 Yes 62 51.2 57 47.1  
BMI (kg/m2)      
 mean (range) 24.0 (16.2–35.4) 23.1 (15.4–38.1) 0.272*
 Normal (<25) 85 70.2 80 64.5 0.627
 Overweight (25–30) 28 23.1 33 27.3  
 Obese (>30) 8 6.6 10 8.3  
  1. a Human epidermal growth factor receptor 2 (Her2) status indicated all Her2 (3+)-positive tumors and Her2 (2+)- positive tumors with Her2 amplification investigated by fluorescence in situ hybridization; ratio ≥ 2. AJCC American Joint Committee on Cancer, MBD mammographic breast density, BMI body mass index. *Significance tested using paired Student’s t test. Significance tested using Pearson’s chi-square test