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Table 5 Multivariate cox regression analysis for predictors of breast cancer specific survival (BCSS) within the whole cohort and the ER+ subgroups

From: ADA3 regulates normal and tumor mammary epithelial cell proliferation through c-MYC

Parameter

In the whole cohort

In ER+ only

P value

HR (95% CI)

P value

HR (95% CI)

ADA3 combinatorial expression

0.040

1.06 (1.01–1.16)

0.001

1.12 (1.05- 1.96)

Tumor grade

0.002

1.44 (1.14 – 183)

0.001

1.49 (1.17 -1.90)

Tumor stage

<0.001

2.11 (1.73- 2.58)

<0.001

2.21 (1.72- 2.84)

Tumor size

0.015

1.14 (1.07- 1.91)

0.069

1.38 (0.98 - 1.96)

ER status

0.971

0.10 (0.71- 1.39)

-

-

  1. HR: Hazard Ratio, CI: confidence interval