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Table 5 Multivariate cox regression analysis for predictors of breast cancer specific survival (BCSS) within the whole cohort and the ER+ subgroups

From: ADA3 regulates normal and tumor mammary epithelial cell proliferation through c-MYC

Parameter In the whole cohort In ER+ only
P value HR (95% CI) P value HR (95% CI)
ADA3 combinatorial expression 0.040 1.06 (1.01–1.16) 0.001 1.12 (1.05- 1.96)
Tumor grade 0.002 1.44 (1.14 – 183) 0.001 1.49 (1.17 -1.90)
Tumor stage <0.001 2.11 (1.73- 2.58) <0.001 2.21 (1.72- 2.84)
Tumor size 0.015 1.14 (1.07- 1.91) 0.069 1.38 (0.98 - 1.96)
ER status 0.971 0.10 (0.71- 1.39) - -
  1. HR: Hazard Ratio, CI: confidence interval
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