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Table 3 Associations between identified dense area features and IC versus SC based on multivariate logistic regression modelling
| Odds ratios (95 % Cl) for interval versus screen-detected cancer, estimated by logistic regression modelling | ||||
|---|---|---|---|---|
| Primary cohort | Validation cohort | |||
| Covariate | Model 1 n = 1403 | Model 2 n = 1314 | Model 3 n = 1312 | Model 3 n = 1182 |
| Percent density | 1.37 (1.22 to 1.53) | 1.23 (1.08 to 1.41) | 0.98 (0,81 to 1.17) | 1.04 (0.86 to 1.24) |
| BMI | - | 0.84 (0.73 to 0.98) | 0.88 (0.76 to 1.02) | 0.98 (0.84 to 1.15) |
| HRT use at diagnosis | - | 1.57 (1.17 to 2.11) | 1.53 (1.14 to 2.07) | 1.32 (0.99 to 1.77) |
| Age at diagnosis | - | 0.98 (0.87 to 1.12) | 1.01 (0.89 to 1.15) | 0.90 (0.77 to 1.05) |
| F40 skewness of the intensity gradient | - | - | 1.32 (1.12 to 1.56) | 1.21 (1.04 to 1.41) |
| F21 eccentricity | - | - | 1.20 (1.04 to 1.39) | 1.17 (0.98 to 1.39) |
