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Table 4 Differentially expressed genes in breast tumors of p.I157T carriers when compared to non-carrier tumors

From: Patient survival and tumor characteristics associated with CHEK2:p.I157T – findings from the Breast Cancer Association Consortium

Gene ID

Symbol

Description

logFC

p value

11283

CYP4F8

Cytochrome P450, family 4, subfamily F, polypeptide 8

1.10

0.00026

1289

COL5A1

Collagen, type V, alpha 1

1.24

0.00049

1292

COL6A2

Collagen, type VI, alpha 2

0.90

0.00056

56265

CPXM1

Carboxypeptidase X (M14 family), member 1

1.04

0.00063

1277

COL1A1

Collagen, type I, alpha 1

1.25

0.0011

23452

ANGPTL2

Angiopoietin-like 2

0.85

0.0020

5118

PCOLCE

Procollagen C-endopeptidase enhancer

0.90

0.0021

284297

SSC5D

Scavenger receptor cysteine rich family, 5 domains

0.84

0.0025

25903

OLFML2B

Olfactomedin-like 2B

0.88

0.0026

27239

GPR162

G protein-coupled receptor 162

0.73

0.0026

5654

HTRA1

HtrA serine peptidase 1

0.96

0.0027

9315

NREP

Neuronal regeneration-related protein

0.78

0.0028

1278

COL1A2

Collagen, type I, alpha 2

1.02

0.0046

8510

MMP23B

Matrix metallopeptidase 23B

0.73

0.0055

114902

C1QTNF5

C1q and tumor necrosis factor-related protein 5

0.77

0.0057

6678

SPARC

Secreted protein, acidic, cysteine-rich (osteonectin)

0.88

0.0073

9622

KLK4

Kallikrein-related peptidase 4

1.03

0.0082

1291

COL6A1

Collagen, type VI, alpha 1

0.92

0.0084

1307

COL16A1

Collagen, type XVI, alpha 1

0.73

0.0090

1290

COL5A2

Collagen, type V, alpha 2

0.93

0.0095

7070

THY1

Thy-1 cell surface antigen

0.88

0.0098

  1. logFC logarithm of fold change