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Table 4 Differentially expressed genes in breast tumors of p.I157T carriers when compared to non-carrier tumors

From: Patient survival and tumor characteristics associated with CHEK2:p.I157T – findings from the Breast Cancer Association Consortium

Gene ID Symbol Description logFC p value
11283 CYP4F8 Cytochrome P450, family 4, subfamily F, polypeptide 8 1.10 0.00026
1289 COL5A1 Collagen, type V, alpha 1 1.24 0.00049
1292 COL6A2 Collagen, type VI, alpha 2 0.90 0.00056
56265 CPXM1 Carboxypeptidase X (M14 family), member 1 1.04 0.00063
1277 COL1A1 Collagen, type I, alpha 1 1.25 0.0011
23452 ANGPTL2 Angiopoietin-like 2 0.85 0.0020
5118 PCOLCE Procollagen C-endopeptidase enhancer 0.90 0.0021
284297 SSC5D Scavenger receptor cysteine rich family, 5 domains 0.84 0.0025
25903 OLFML2B Olfactomedin-like 2B 0.88 0.0026
27239 GPR162 G protein-coupled receptor 162 0.73 0.0026
5654 HTRA1 HtrA serine peptidase 1 0.96 0.0027
9315 NREP Neuronal regeneration-related protein 0.78 0.0028
1278 COL1A2 Collagen, type I, alpha 2 1.02 0.0046
8510 MMP23B Matrix metallopeptidase 23B 0.73 0.0055
114902 C1QTNF5 C1q and tumor necrosis factor-related protein 5 0.77 0.0057
6678 SPARC Secreted protein, acidic, cysteine-rich (osteonectin) 0.88 0.0073
9622 KLK4 Kallikrein-related peptidase 4 1.03 0.0082
1291 COL6A1 Collagen, type VI, alpha 1 0.92 0.0084
1307 COL16A1 Collagen, type XVI, alpha 1 0.73 0.0090
1290 COL5A2 Collagen, type V, alpha 2 0.93 0.0095
7070 THY1 Thy-1 cell surface antigen 0.88 0.0098
  1. logFC logarithm of fold change