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Table 2 Phenotypic classification of breast tumors from ten carriers of p.I157T

From: Patient survival and tumor characteristics associated with CHEK2:p.I157T – findings from the Breast Cancer Association Consortium

  Intrinsic subtype PAM50 IHC subtype St Gallen 2013 criteria Histological type
HEL_045 Normal LumA Lobular
HEL_055 LumB LumB Ductal
HEL_086 LumA LumA Lobular
HEL_126 LumA Basal Ductal
HEL_128 LumA LumB Ductal
HEL_131 Basal Her2pos In situ
HEL_144 Normal LumB Lobular
HEL_150 Basal LumB Ductal
HEL_163 LumB LumB Ductal
HEL_174 Normal LumA Lobular
  1. IHC immunohistochemistry, LumB luminal B, LumA luminal A, Her2 human epidermal growth factor receptor 2