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Table 2 Phenotypic classification of breast tumors from ten carriers of p.I157T

From: Patient survival and tumor characteristics associated with CHEK2:p.I157T – findings from the Breast Cancer Association Consortium

 

Intrinsic subtype PAM50

IHC subtype St Gallen 2013 criteria

Histological type

HEL_045

Normal

LumA

Lobular

HEL_055

LumB

LumB

Ductal

HEL_086

LumA

LumA

Lobular

HEL_126

LumA

Basal

Ductal

HEL_128

LumA

LumB

Ductal

HEL_131

Basal

Her2pos

In situ

HEL_144

Normal

LumB

Lobular

HEL_150

Basal

LumB

Ductal

HEL_163

LumB

LumB

Ductal

HEL_174

Normal

LumA

Lobular

  1. IHC immunohistochemistry, LumB luminal B, LumA luminal A, Her2 human epidermal growth factor receptor 2