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Table 1 microRNAs selectively secreted to exosomes from mammary epithelial cells and breast cancer cells

From: Plasma exosome microRNAs are indicative of breast cancer

MCF10A MCF7 MDA-MB-231
microRNA Fold-change Mean reads microRNA Fold-change Mean reads microRNA Fold-change Mean reads
hsa-mir-4508 333.36 94.73 hsa-mir-3662 1136.26 375.59 hsa-mir-143 126.92 11.87
hsa-mir-320e 19.64 446.61 hsa-mir-122 227.25 751.19 hsa-mir-589 19.61 18.34
hsa-mir-320d-1 18.70 478.18 hsa-mir-1246 130.37 10773.97 hsa-mir-33a 16.15 15.10
hsa-mir-1246 16.73 1236.06 hsa-mir-142 105.21 34.78 hsa-mir-29a 9.46 44.22
hsa-mir-320c-1 16.67 1231.55 hsa-mir-1290 105.21 34.78 hsa-mir-1246 8.61 2181.03
hsa-mir-4516 12.17 103.76 hsa-mir-451 20.34 201.71 hsa-mir-324 8.46 23.73
hsa-mir-193a 8.33 94.73   hsa-mir-16-1 6.11 3398.83
hsa-mir-320b-1 6.70 6148.72  
hsa-mir-92b 6.07 3848.03  
  1. The microRNAs with a fold-change ≥6.0 in the exosome vs. the cellular content and mapped reads ≥30 are shown. The fold-change was calculated by normalizing the reads to the number of mapped reads. microRNAs in bold were further evaluated in this study