Fig. 2
From: Plasma exosome microRNAs are indicative of breast cancer
Small RNA next generation sequencing analysis of microRNAs in mammary epithelial cells and breast cancer cell lines versus exosomes. Cellular and exosome RNA was isolated from normal mammary cells (MCF10A) and breast cancer cell lines (MCF7 and MDA-MB-231). microRNAs were differentially expressed in MCF10A (a), MCF7 (c) and MDA-MB-231 (e) exosomes with a fold-change ≥6.0 (exosome vs. cell, p < 0.05) with mapped reads ≥ 200 are plotted. The abundance of the microRNAs highly expressed in exosomes vs. the cellular RNA in MCF10A (b), MCF7 (d) and MDA-MB-231 (f) are plotted by their mean number of reads per million reads