From: Mammographic density and breast cancer risk: a mediation analysis
 | Premenopausal | Postmenopausal | ||
---|---|---|---|---|
 | Cases N = 559 | Controls N = 1727 | Cases N = 731 | Controls N = 1695 |
Mean (SD) | ||||
 Agea | 46.2 (4.6) | 46.1 (4.3) | 60.1 (7.0) | 59.6 (7.4) |
 Current BMI (kg/m2) | 25.2 (4.8) | 25.4 (5.1) | 25.9 (4.6) | 26.1 (5.0) |
 Childhood somatotype | 2.5 (1.2) | 2.6 (1.2) | 2.2 (1.2) | 2.4 (1.3) |
 Adolescent somatotype | 2.8 (1.0) | 2.9 (1.1) | 2.5 (1.1) | 2.7 (1.2) |
 BMI at age 18 (kg/m2) | 20.8 (2.5) | 21.1 (2.7) | 20.9 (2.4) | 21.1 (2.7) |
 Weight change since 18 (lbs) | 26.7 (25.8) | 26.3 (25.7) | 29.7 (25.4) | 29.7 (26.8) |
 Age at menarche | 12.3 (1.4) | 12.4 (1.4) | 12.5 (1.4) | 12.6 (1.4) |
 Parity (among parous) | 2.4 (1.0) | 2.5 (1.0) | 3.2 (1.5) | 3.2 (1.5) |
 Age at first birth (among parous) | 26.3 (4.4) | 25.9 (4.1) | 25.6 (3.7) | 25.2 (3.5) |
 Breastfeeding (months)  (among parous women who ever breastfed) | 16.3 (10.6) | 17.1 (11.1) | 12.6 (10.8) | 11.4 (9.5) |
 Birth index | 46.0 (26.4) | 46.7 (25.9) | 56.4 (37.4) | 55.8 (37.7) |
 Height (inches) | 65.1 (2.6) | 64.9 (2.5) | 64.5 (2.3) | 64.6 (2.4) |
 Alcohol use (g/day) | 4.2 (6.9) | 4.2 (6.3) | 5.0 (7.5) | 4.8 (7.8) |
 Age at menopause (y) |  |  | 47.8 (5.8) | 46.7 (6.5) |
 Percent density | 46.1 (18.7) | 39.7 (19.0) | 29.2 (17.6) | 24.8 (17.2) |
 Dense area (cm2) | 96.8 (57.5) | 81.3 (50.8) | 50.7 (38.4) | 47.1 (38.9) |
 Non-dense area (cm2) | 121.4 (77.0) | 134.4 (80.4) | 141.3 (90.3) | 157.5 (91.1) |
N (percent) | ||||
 Nulliparous | 81 (14.5) | 228 (13.2) | 65 (8.9) | 139 (8.2) |
 Ever breastfed (among parous) | 361 (76.5) | 1136 (76.9) | 389 (53.6) | 940 (55.8) |
 Personal history of BBD | ||||
  Confirmed by biopsy | 154 (27.5) | 287 (16.6) | 193 (26.4) | 382 (22.5) |
  Unconfirmed/unknown | 170 (30.4) | 566 (32.8) | 190 (26.0) | 423 (25.0) |
 Family history of breast cancer | 67 (12.0) | 146 (8.5) | 132 (18.1) | 225 (13.3) |
 Hormone therapy usea | ||||
  Never |  |  | 191 (26.1) | 547 (32.3) |
  Current |  |  | 401 (54.9) | 789 (46.5) |
  Past |  |  | 139 (19.0) | 359 (21.2) |