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Fig. 6 | Breast Cancer Research

Fig. 6

From: PRKCQ promotes oncogenic growth and anoikis resistance of a subset of triple-negative breast cancer cells

Fig. 6

Treatment with AEB071 inhibits protein kinase C (PKC)θ activity and impairs growth of triple-negative breast cancer cells. a MDA-231-Luc-D3H2LN cells were treated with AEB071 at the indicated concentrations for 24 hours. Cells were lysed and probed with antibodies that recognize autophosphorylated PKC isoforms. b MDA-231-Luc-D3H2LN cells were treated with the indicated concentrations of AEB071 in 3-D Matrigel™ cultures for 7 days with refeeding every 2–3 days. Scale bar indicates 200 μM. DMSO dimethyl sulfoxide

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Breast Cancer Research

ISSN: 1465-542X

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