Skip to main content
Fig. 2 | Breast Cancer Research

Fig. 2

From: Combination of Paclitaxel and MG1 oncolytic virus as a successful strategy for breast cancer treatment

Fig. 2

Paclitaxel (PAC) enhances MG1 in various human and mouse breast tumor cell lines. a Microscopy images of EMT6, 4 T1 and EO771 tumor cells infected with MG1-green fluorescent protein (GFP) after a 4-h pre-treatment with 2 uM PAC. Graphs right represent virus titers obtained 24 h post infection. ND no drug, pfu plaque-forming units. b Microscopy images of MDA-MB-231, BT-549 and Hs578T human tumor cells infected with MG1-GFP after a 4-h pre-treatment with 2 uM PAC. Flow cytometry histograms show the GFP expression of infected EMT6 (c) or (d) 4 T1 cells 24 h post infection with or without PAC pre-treatment. The right graphs show percentage of GFP+ cells and the mean fluorescence values (MFV). Samples were analyzed in triplicates. Statistical significance was tested using the unpaired two-tailed t test with Welch’s correction; *p < 0.05, **p < 0.01 ***p < 0.001. Ctrl control

Back to article page