From: Tumor-associated stromal cells as key contributors to the tumor microenvironment
 | Dysregulation in TASCs | Regulator of TAF transition | Regulator of stromal cell recruitment | Mediates TASC-induced therapeutic resistance |
---|---|---|---|---|
IGFBP-2 | [21] | - | - | - |
MMP-11 | [22] | - | - | - |
IL-6 | [35] | |||
IL-8 | [40] | - | - | - |
IL-1beta | [40] | - | - | |
TNF-alpha | [31] | - | - | |
NF-kappaB | [24] | - | - | - |
TGF-beta | [39] | - | - | - |
CXCL1/2 | - | - | ||
FAP | [35] | - | - | - |
MCP-1 | [40] | - | - | - |
Twist1 | - | - | - | |
miR-21 | [43] | [44] | - | - |
miR-221/222 | [44] | [44] | - | [46] |
MAPK/ERK | [45] | - | - | - |
miR-15a/16 | [47] | - | - | - |
miR-210 | [51] | [51] | - | - |
Exosomes | - | - | [58] | |
mTOR-4E-BP-1 | - | - | - | [38] |
miR-126/126* | - | - | [52] | - |
miR-149 | - | - | [33] | - |
miR-155 | - | - | - | |
miR-31 | - | [50] | - | - |
miR-214 | - | [50] | - | - |