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Table 6 A summary of genes significantly upregulated in samples of BRCA1 mutation carriers compared to non-carriers (Benjamini-Hochberg false discovery rate < 0.05 using the t test)

From: Reduced BRCA1 transcript levels in freshly isolated blood leukocytes from BRCA1 mutation carriers is mutation specific

Gene Gene name P value
CLTC Clathrin, heavy chain (Hc) 0.000
FLT3 Fms-related tyrosine kinase 3 0.002
LMO2 LIM domain only 2 0.002
REL V-Rel avian reticuloendotheliosis viral oncogene homolog 0.002
BCR Breakpoint cluster region 0.004
PTPN11 Protein tyrosine phosphatase, non-receptor type 11 0.004
TNFRSF10B Tumor necrosis factor superfamily, member 10B 0.007
IL8 Interleukin 8 0.009
TGFB1 Transforming growth factor, beta 1 0.009