Table 6 A summary of genes significantly upregulated in samples of BRCA1 mutation carriers compared to non-carriers (Benjamini-Hochberg false discovery rate < 0.05 using the t test)
Gene | Gene name | P value |
|---|---|---|
CLTC | Clathrin, heavy chain (Hc) | 0.000 |
FLT3 | Fms-related tyrosine kinase 3 | 0.002 |
LMO2 | LIM domain only 2 | 0.002 |
REL | V-Rel avian reticuloendotheliosis viral oncogene homolog | 0.002 |
BCR | Breakpoint cluster region | 0.004 |
PTPN11 | Protein tyrosine phosphatase, non-receptor type 11 | 0.004 |
TNFRSF10B | Tumor necrosis factor superfamily, member 10B | 0.007 |
IL8 | Interleukin 8 | 0.009 |
TGFB1 | Transforming growth factor, beta 1 | 0.009 |