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Table 5 A summary of genes significantly downregulated in samples of BRCA1 mutation carriers compared to non-carriers (Benjamini-Hochberg false discovery rate < 0.05 using the t-test)

From: Reduced BRCA1 transcript levels in freshly isolated blood leukocytes from BRCA1 mutation carriers is mutation specific

Gene Gene name P value
CSK c-Src tyrosine kinase 0.000
NRAS Neuroblastoma RAS viral (v-ras) oncogene homolog 0.000
TGFBR2 Transforming growth factor, beta receptor II 0.001
XPC Xeroderma pigmentosum, complementation group C 0.001
BRCA1 Breast cancer 1, early onset 0.002
PCTK1/CDK16 Cyclin-dependent kinase 16 0.008
TOP1 Topoisomerase (DNA) I 0.008
TNFSF10 Tumor necrosis factor (ligand) superfamily, member 10 0.009