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Table 2 Correlation between reproductive or lifestyle factors and BRCA1 mRNA expression

From: Reduced BRCA1 transcript levels in freshly isolated blood leukocytes from BRCA1 mutation carriers is mutation specific

Variable Unstandardized B (95 % CI) P value
Age −0.63 (−1.3, 0.07) 0.08
Parity (ever) −22.3 (−40, −4.8) 0.01
Breastfeeding (ever) −12 (−22, −3) 0.009
Age at menarche −3.7 (−10.2, 2.8) 0.30
Menopause −23.3 (−43, −4) 0.02
Current oral contraceptive use −2.5 (−33, 30) 0.90
Current smoking status −9.3 (−45, 26) 0.60
Current alcohol consumption 0.115 (−28, 28) 1.00
Mastectomy −15.3 (−41, 10) 0.23
Oophorectomy −24 (−45, −3.4) 0.02
Current hormone replacement therapy use 0.5 (−11.8, 12.8) 0.93
Body mass index 0.445 (−1.5, 2.3) 0.65
Mutation status −28.5 (−46, −11) 0.002
  1. Data are provided as linear regression coefficient, Unstandardized B coefficient and 95 % confidence intervals. P value < 0.05 denotes statistical significance