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Fig. 2 | Breast Cancer Research

Fig. 2

From: MicroRNA expression and gene regulation drive breast cancer progression and metastasis in PyMT mice

Fig. 2

Transition patterns of microRNA (miRNA) expression during cancer progression. Each gray line, re-based to 0 at week 6, shows the pseudo fold-changes (ϕFCs) of a particular miRNA at the four assayed time points. Expression change during each stage transition was discretized into increase (+), no change (0), or decrease (–). All miRNAs with the same transition pattern, e.g., p–00, are plotted together in one plot, in which the transition pattern and the number of miRNAs are given at the top. The red line in each plot indicates the median ϕFCs. Only positive and negative patterns without opposite changes are shown here. See Additional file 1: Figure S2 for the whole set of 27 transition patterns

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