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Table 1 Health parameters of male rats and their 50-day-old female offspring in control diet, lard-based diet, and corn oil-based diet groups

From: Paternal programming of breast cancer risk in daughters in a rat model: opposing effects of animal- and plant-based high-fat diets

 

CO

LB

CB

Male rats

   

 Weight gain

363.1 ± 6.4 g

398.2 ± 12.0 ga

369.4 ± 7.8 gb

 Fat weight

  Abdominal fat

1.4 ± 0.1 g/100 g body weight

2.7 ± 0.2 g/100 g body weighta

2.6 ± 0.2 g/100 g body weighta

  Retroperitoneal fat

0.8 ± 0.1 g/100 g body weight

1.9 ± 0.1 g/100 g body weighta

1.7 ± 0.2 g/100 g body weighta

  Epididymal fat

1.2 ± 0.1 g/100 g body weight

2.7 ± 0.1 g/100 g body weighta

2.0 ± 0.2 g/100 g body weighta,b

 Reproductive organs

  Testicle

0.45 ± 0.01 g/100 g body weight

0.40 ± 0.01 g/100 g body weighta

0.45 ± 0.01 g/100 g body weightb

  Epididymis

0.14 ± 0.00 g/100 g body weight

0.13 ± 0.00 g/100 g body weighta

0.14 ± 0.00 g/100 g body weightb

  Seminal vesicle

0.33 ± 0.01 g/100 g body weight

0.29 ± 0.02 g/100 g body weightc

0.33 ± 0.02 g/100 g body weightd

 Sperm morphology (% normal)

66.4 ± 2.8 %

50.1 ± 3.0 %a

70.9 ± 2.9 %b

 Daily sperm production, n/testicle/day

31 ± 1.9 × 106

23 ± 0.9a × 106

29 ± 0.8b × 106

 Fasting glycemia

100.8 ± 3 mg/dl

124.6 ± 4 mg/dla

116.1 ± 3 mg/dla

50-day-old female offspring

   

 Birth weight

8.0 ± 1.5 g

8.8 ± 1.0 ga

9.1 ± 1.5 ga

 Weight gain

138.9 ± 1.5 g

147.0 ± 1.2 ga

142.1 ± 1.1 gb,c

 Retroperitoneal fat

0.9 ± 0.1 g/100 g body weight

1.1 ± 0.0 g/100 g body weighta

1.2 ± 0.1 g/100 g body weighta

 Fasting glycemia

106.4 ± 2.0 mg/dl

112.5 ± 1.9 mg/dla

106.3 ± 1.2 mg/dlb

  1. Abbreviations: CB rats fed a corn oil-based high-fat diet and their offspring, CO rats fed a control diet and their offspring, LB rats fed a lard-based high-fat diet and their offspring
  2. Statistically significant difference (p ≤ 0.05) compared with aCO and bLB, according to analysis of variance followed by least significant difference test. Marginal difference (p ≤ 0.08) compared with cCO and dLB, according to t test. The data are expressed as mean ± SEM (n = 20 per group)