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Fig. 5 | Breast Cancer Research

Fig. 5

From: Genome co-amplification upregulates a mitotic gene network activity that predicts outcome and response to mitotic protein inhibitors in breast cancer

Fig. 5

Dose response in breast cancer subtypes. Responses to GSK462364, GSK923295, and GSK1070916 were assayed for compounds individually or in combination in cell lines representing different breast cancer subtypes. a Responses in cell lines with a high mitotic network activity index (MNAI) and a low MNAI, and b responses in basal and luminal breast cancer cell lines were assessed using the two-tailed Mann-Whitney U test. c Responses to GSK462364, GSK923295 and GSK1070916 administered individually or in pairwise combination in breast cancer cell lines with high (HCC38) or low (MDAMB175) MNAI

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Breast Cancer Research

ISSN: 1465-542X

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