TY - JOUR AU - Gaillard, H. AU - García-Muse, T. AU - Aguilera, A. PY - 2015 DA - 2015// TI - Replication stress and cancer JO - Nat Rev Cancer. VL - 15 UR - https://doi.org/10.1038/nrc3916 DO - 10.1038/nrc3916 ID - Gaillard2015 ER - TY - JOUR AU - Vader, G. AU - Lens, S. M. PY - 1785 DA - 1785// TI - The Aurora kinase family in cell division and cancer JO - Biochim Biophys Acta. VL - 2008 ID - Vader1785 ER - TY - JOUR AU - Curtis, C. PY - 2015 DA - 2015// TI - Genomic profiling of breast cancers JO - Curr Opin Obstet Gynecol VL - 27 UR - https://doi.org/10.1097/GCO.0000000000000145 DO - 10.1097/GCO.0000000000000145 ID - Curtis2015 ER - TY - JOUR AU - Carter, S. L. AU - Eklund, A. C. AU - Kohane, I. S. AU - Harris, L. N. AU - Szallasi, Z. PY - 2006 DA - 2006// TI - A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers JO - Nat Genet. VL - 38 UR - https://doi.org/10.1038/ng1861 DO - 10.1038/ng1861 ID - Carter2006 ER - TY - JOUR AU - Medri, L. AU - Volpi, A. AU - Nanni, O. AU - Vecci, A. M. AU - Mangia, A. AU - Schittulli, F. PY - 2003 DA - 2003// TI - Prognostic relevance of mitotic activity in patients with node-negative breast cancer JO - Mod Pathol. VL - 15 ID - Medri2003 ER - TY - JOUR AU - Strebhardt, K. AU - Becker, S. AU - Matthess, Y. PY - 2015 DA - 2015// TI - Thoughts on the current assessment of Polo-like kinase inhibitor drug discovery JO - Expert Opin Drug Discov VL - 10 UR - https://doi.org/10.1517/17460441.2015.962510 DO - 10.1517/17460441.2015.962510 ID - Strebhardt2015 ER - TY - JOUR AU - Barr, F. A. AU - Sillje, H. H. AU - Nigg, E. A. PY - 2004 DA - 2004// TI - Polo-like kinases and the orchestration of cell division JO - Nat Rev Mol Cell Biol VL - 5 UR - https://doi.org/10.1038/nrm1401 DO - 10.1038/nrm1401 ID - Barr2004 ER - TY - JOUR AU - Toyoshima-Morimoto, F. AU - Taniguchi, E. AU - Shinya, N. AU - Iwamatsu, A. AU - Nishida, E. PY - 2001 DA - 2001// TI - Polo-like kinase 1 phosphorylates cyclin B1 and targets it to the nucleus during prophase JO - Nature. VL - 410 UR - https://doi.org/10.1038/35065617 DO - 10.1038/35065617 ID - Toyoshima-Morimoto2001 ER - TY - JOUR AU - McInnes, C. AU - Mazumdar, A. AU - Mezena, M. AU - Meades, C. AU - Midgley, C. AU - Scaerou, F. PY - 2005 DA - 2005// TI - Inhibitors of Polo-like kinase reveal roles in spindle-pole maintenance JO - Nat Chem Biol. VL - 2 ID - McInnes2005 ER - TY - JOUR AU - Yamada, S. AU - Ohira, M. AU - Horie, H. AU - Ando, K. AU - Takayasu, H. AU - Suzuki, Y. PY - 2004 DA - 2004// TI - Expression profiling and differential screening between hepatoblastomas and the corresponding normal livers: identification of high expression of the PLK1 oncogene as a poor-prognostic indicator of hepatoblastomas JO - Oncogene. VL - 23 UR - https://doi.org/10.1038/sj.onc.1207782 DO - 10.1038/sj.onc.1207782 ID - Yamada2004 ER - TY - JOUR AU - Li, Y. AU - Zhang, Z. F. AU - Chen, J. AU - Huang, D. AU - Ding, Y. AU - Tan, M. H. PY - 2010 DA - 2010// TI - VX580/MK-0457, a potent and selective Aurora kinase inhibitor, targets both tumor and endothelial cells in clear cell renal cell carcinoma JO - Am J Transl Res. VL - 2 ID - Li2010 ER - TY - JOUR AU - Curry, J. AU - Angove, H. AU - Fazal, L. AU - Lyons, J. AU - Reule, M. AU - Thompson, N. PY - 2009 DA - 2009// TI - Aurora B kinase inhibition in mitosis: strategies for optimising the use of aurora kinase inhibitors such as AT9283 JO - Cell Cycle. VL - 8 UR - https://doi.org/10.4161/cc.8.12.8741 DO - 10.4161/cc.8.12.8741 ID - Curry2009 ER - TY - JOUR AU - Wood, K. W. AU - Chua, P. AU - Sutton, D. AU - Jackson, J. R. PY - 2010 DA - 2010// TI - Antitumor activity of an allosteric inhibitor of centromere-associated protein-E JO - Proc Natl Acad Sci USA VL - 107 UR - https://doi.org/10.1073/pnas.0915068107 DO - 10.1073/pnas.0915068107 ID - Wood2010 ER - TY - JOUR AU - Pérez-Melero, C. PY - 2014 DA - 2014// TI - KSP inhibitors as antimitotic agents JO - Curr Top Med Chem. VL - 14 UR - https://doi.org/10.2174/1568026614666141130095532 DO - 10.2174/1568026614666141130095532 ID - Pérez-Melero2014 ER - TY - JOUR AU - Quigley, D. A. AU - To, M. D. AU - Perez-Losada, J. AU - Pelorosso, F. G. AU - Mao, J. H. AU - Nagase, H. PY - 2009 DA - 2009// TI - Genetic architecture of mouse skin inflammation and tumour susceptibility JO - Nature. VL - 458 UR - https://doi.org/10.1038/nature07683 DO - 10.1038/nature07683 ID - Quigley2009 ER - TY - JOUR AU - Ewart-Toland, A. AU - Briassouli, P. AU - Koning, J. P. AU - Mao, J. H. AU - Yuan, J. AU - Chan, F. PY - 2003 DA - 2003// TI - Identification of Stk5/STK15 as a candidate low-penetrance tumor-susceptibility gene in mouse and human JO - Nat Genet. VL - 34 UR - https://doi.org/10.1038/ng1220 DO - 10.1038/ng1220 ID - Ewart-Toland2003 ER - TY - JOUR AU - Balmain, A. AU - Gray, J. AU - Ponder, B. PY - 2003 DA - 2003// TI - The genetics and genomics of cancer JO - Nat Genet VL - 33 UR - https://doi.org/10.1038/ng1107 DO - 10.1038/ng1107 ID - Balmain2003 ER - TY - JOUR AU - Schoffski, P. PY - 2009 DA - 2009// TI - Polo-like kinase (PLK) inhibitors in preclinical and early clinical development in oncology JO - Oncologist. VL - 14 UR - https://doi.org/10.1634/theoncologist.2009-0010 DO - 10.1634/theoncologist.2009-0010 ID - Schoffski2009 ER - TY - JOUR AU - Gilmartin, A. G. AU - Bleam, M. R. AU - Richter, M. C. AU - Erskine, S. G. AU - Kruger, R. G. AU - Madden, L. PY - 2009 DA - 2009// TI - Distinct concentration-dependent effects of the polo-like kinase 1-specific inhibitor GSK462364A, including differential effect on apoptosis JO - Cancer Res. VL - 59 ID - Gilmartin2009 ER - TY - JOUR AU - Wood, K. W. AU - Chua, P. AU - Sutton, D. AU - Jackson, J. R. PY - 2008 DA - 2008// TI - Centromere-associated protein E: a motor that puts the brakes on the mitotic checkpoint JO - Clin Cancer Res. VL - 14 UR - https://doi.org/10.1158/1078-0432.CCR-07-4443 DO - 10.1158/1078-0432.CCR-07-4443 ID - Wood2008 ER - TY - JOUR AU - Anderson, K. AU - Lai, Z. AU - McDonald, O. B. AU - Stuart, J. D. AU - Nartey, E. N. AU - Hardwicke, M. A. PY - 2009 DA - 2009// TI - Biochemical characterization of GSK1070916, a potent and selective inhibitor of Aurora B and Aurora C kinases with an extremely long residence time JO - Biochem J. VL - 420 UR - https://doi.org/10.1042/BJ20090121 DO - 10.1042/BJ20090121 ID - Anderson2009 ER - TY - JOUR AU - Adams, N. D. AU - Adams, J. L. AU - Burgess, J. L. AU - Chaudhari, A. M. AU - Copeland, R. A. AU - Donatelli, C. A. PY - 2010 DA - 2010// TI - Discovery of GSK1070916, a potent and selective inhibitor of Aurora B/C kinase JO - J Med Chem. VL - 53 UR - https://doi.org/10.1021/jm901870q DO - 10.1021/jm901870q ID - Adams2010 ER - TY - JOUR AU - Neve, R. M. AU - Chin, K. AU - Fridlyand, J. AU - Yeh, J. AU - Baehner, F. L. AU - Fevr, T. PY - 2005 DA - 2005// TI - A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes JO - Cancer Cell. VL - 10 UR - https://doi.org/10.1016/j.ccr.2006.10.008 DO - 10.1016/j.ccr.2006.10.008 ID - Neve2005 ER - TY - JOUR AU - Wiel, M. A. AU - Wieringen, W. N. PY - 2007 DA - 2007// TI - CGH regions: dimension reduction for array CGH data with minimal information loss JO - Cancer Inform. VL - 3 ID - Wiel2007 ER - TY - JOUR AU - Barbosa-Morais, N. L. AU - Dunning, M. J. AU - Samarajiwa, S. A. AU - Darot, J. F. AU - Ritchie, M. E. AU - Lynch, A. G. PY - 2009 DA - 2009// TI - A re-annotation pipeline for Illumina Bead Arrays: improving the interpretation of gene expression data JO - Nucleic Acids Res VL - 38 UR - https://doi.org/10.1093/nar/gkp942 DO - 10.1093/nar/gkp942 ID - Barbosa-Morais2009 ER - TY - JOUR AU - Korde, L. A. AU - Lusa, L. AU - McShane, L. AU - Lebowitz, P. F. AU - Lukes, L. AU - Camphausen, K. PY - 2010 DA - 2010// TI - Gene expression pathway analysis to predict response to neoadjuvant docetaxel and capecitabine for breast cancer JO - Breast Cancer Res Treat VL - 119 UR - https://doi.org/10.1007/s10549-009-0651-3 DO - 10.1007/s10549-009-0651-3 ID - Korde2010 ER - TY - JOUR AU - Curtis, C. AU - Shah, S. P. AU - Chin, S. F. AU - Turashvili, G. AU - Rueda, O. M. AU - Dunning, M. J. PY - 2012 DA - 2012// TI - The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups JO - Nature. VL - 486 ID - Curtis2012 ER - TY - JOUR AU - Maere, S. AU - Heymans, K. AU - Kuiper, M. PY - 2005 DA - 2005// TI - BiNGO: a Cytoscape plugin to assess overrepresentation of gene ontology categories in biological networks JO - Bioinformatics VL - 21 UR - https://doi.org/10.1093/bioinformatics/bti551 DO - 10.1093/bioinformatics/bti551 ID - Maere2005 ER - TY - JOUR AU - Kel, A. E. AU - Gössling, E. AU - Reuter, I. AU - Cheremushkin, E. AU - Kel-Margoulis, O. V. AU - Wingender, E. PY - 2003 DA - 2003// TI - MATCH: a tool for searching transcription factor binding sites in DNA sequences JO - Nucleic Acids Res. VL - 31 UR - https://doi.org/10.1093/nar/gkg585 DO - 10.1093/nar/gkg585 ID - Kel2003 ER - TY - JOUR AU - Krull, M. AU - Voss, N. AU - Choi, C. AU - Pistor, S. AU - Potapov, A. AU - Wingender, E. PY - 2003 DA - 2003// TI - TRANSPATH: an integrated database on signal transduction and a tool for array analysis JO - Nucleic Acids Res. VL - 31 UR - https://doi.org/10.1093/nar/gkg089 DO - 10.1093/nar/gkg089 ID - Krull2003 ER - TY - JOUR AU - Wang, Y. AU - Klijn, J. G. AU - Zhang, Y. AU - Sieuwerts, A. M. AU - Look, M. P. AU - Yang, F. PY - 2005 DA - 2005// TI - Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer JO - Lancet VL - 355 ID - Wang2005 ER - TY - JOUR AU - Pawitan, Y. AU - Bjohle, J. AU - Amler, L. AU - Borg, A. L. AU - Egyhazi, S. AU - Hall, P. PY - 2005 DA - 2005// TI - Gene expression profiling spares early breast cancer patients from adjuvant therapy: derived and validated in two population-based cohorts JO - Breast Cancer Res. VL - 7 UR - https://doi.org/10.1186/bcr1325 DO - 10.1186/bcr1325 ID - Pawitan2005 ER - TY - JOUR AU - Ivshina, A. V. AU - George, J. AU - Senko, O. AU - Mow, B. AU - Putti, T. C. AU - Smeds, J. PY - 2005 DA - 2005// TI - Genetic reclassification of histologic grade delineates new clinical subtypes of breast cancer JO - Cancer Res. VL - 55 ID - Ivshina2005 ER - TY - JOUR AU - Manders, P. AU - Bult, P. AU - Sweep, C. G. AU - Tjan-Heijnen, V. C. AU - Beex, L. V. PY - 2003 DA - 2003// TI - The prognostic value of the mitotic activity index in patients with primary breast cancer who were not treated with adjuvant systemic therapy JO - Breast Cancer Res Treat. VL - 77 UR - https://doi.org/10.1023/A:1021138801890 DO - 10.1023/A:1021138801890 ID - Manders2003 ER - TY - JOUR AU - Russ, A. P. AU - Lampel, S. PY - 2005 DA - 2005// TI - The druggable genome: an update JO - Drug Discov Today. VL - 10 UR - https://doi.org/10.1016/S1359-6446(05)03666-4 DO - 10.1016/S1359-6446(05)03666-4 ID - Russ2005 ER - TY - JOUR AU - Hoar, K. AU - Chakravarty, A. AU - Rabino, C. AU - Wysong, D. AU - Bowman, D. AU - Roy, N. PY - 2007 DA - 2007// TI - MLN8054, a small-molecule inhibitor of Aurora A, causes spindle pole and chromosome congression defects leading to aneuploidy JO - Mol Cell Biol. VL - 27 UR - https://doi.org/10.1128/MCB.02364-06 DO - 10.1128/MCB.02364-06 ID - Hoar2007 ER - TY - JOUR AU - Hirsch, C. L. AU - Coban Akdemir, Z. AU - Wang, L. AU - Jayakumaran, G. AU - Trcka, D. AU - Weiss, A. PY - 2015 DA - 2015// TI - Myc and SAGA rewire an alternative splicing network during early somatic cell reprogramming JO - Genes Dev VL - 29 UR - https://doi.org/10.1101/gad.255109.114 DO - 10.1101/gad.255109.114 ID - Hirsch2015 ER - TY - JOUR AU - Wang, Y. AU - Wen, M. AU - Kwon, Y. AU - Xu, Y. AU - Liu, Y. AU - Zhang, P. PY - 2014 DA - 2014// TI - CUL4A induces epithelial-mesenchymal transition and promotes cancer metastasis by regulating ZEB1 expression JO - Cancer Res. VL - 74 UR - https://doi.org/10.1158/0008-5472.CAN-13-2182 DO - 10.1158/0008-5472.CAN-13-2182 ID - Wang2014 ER - TY - JOUR AU - Liu, J. A. AU - Wu, M. H. AU - Yan, C. H. AU - Chau, B. K. AU - So, H. AU - Ng, A. PY - 2013 DA - 2013// TI - Phosphorylation of Sox9 is required for neural crest delamination and is regulated downstream of BMP and canonical Wnt signaling JO - Proc Natl Acad Sci USA VL - 110 UR - https://doi.org/10.1073/pnas.1211747110 DO - 10.1073/pnas.1211747110 ID - Liu2013 ER - TY - JOUR AU - Martini, S. AU - Bernoth, K. AU - Main, H. AU - Ortega, G. D. AU - Lendahl, U. AU - Just, U. PY - 2013 DA - 2013// TI - A critical role for Sox9 in notch-induced astrogliogenesis and stem cell maintenance JO - Stem Cells. VL - 31 UR - https://doi.org/10.1002/stem.1320 DO - 10.1002/stem.1320 ID - Martini2013 ER - TY - JOUR AU - Bergamaschi, A. AU - Madak-Erdogan, Z. AU - Kim, Y. J. AU - Choi, Y. L. AU - Lu, H. AU - Katzenellenbogen, B. S. PY - 2014 DA - 2014// TI - The forkhead transcription factor FOXM1 promotes endocrine resistance and invasiveness in estrogen receptor-positive breast cancer by expansion of stem-like cancer cells JO - Breast Cancer Res. VL - 16 UR - https://doi.org/10.1186/s13058-014-0436-4 DO - 10.1186/s13058-014-0436-4 ID - Bergamaschi2014 ER - TY - JOUR AU - Dai, H. AU - Veer, L. AU - Lamb, J. AU - He, Y. D. AU - Mao, M. AU - Fine, B. M. PY - 2005 DA - 2005// TI - A cell proliferation signature is a marker of extremely poor outcome in a subpopulation of breast cancer patients JO - Cancer Res. VL - 65 UR - https://doi.org/10.1158/0008-5472.CAN-04-3953 DO - 10.1158/0008-5472.CAN-04-3953 ID - Dai2005 ER - TY - JOUR AU - Starmans, M. H. AU - Krishnapuram, B. AU - Steck, H. AU - Horlings, H. AU - Nuyten, D. S. AU - Vijver, M. J. PY - 2008 DA - 2008// TI - Robust prognostic value of a knowledge-based proliferation signature across large patient microarray studies spanning different cancer types JO - Br J Cancer. VL - 99 UR - https://doi.org/10.1038/sj.bjc.6604746 DO - 10.1038/sj.bjc.6604746 ID - Starmans2008 ER - TY - JOUR AU - Yang, D. AU - Liu, H. AU - Goga, A. AU - Kim, S. AU - Yuneva, M. AU - Bishop, J. PY - 2010 DA - 2010// TI - Therapeutic potential of a synthetic lethal interaction between the MYC proto-oncogene and inhibition of aurora-B kinase JO - Proc Natl Acad Sci. VL - 07 UR - https://doi.org/10.1073/pnas.1008366107 DO - 10.1073/pnas.1008366107 ID - Yang2010 ER - TY - JOUR AU - Hardwicke, M. A. AU - Oleykowski, C. A. AU - Plant, R. AU - Wang, J. AU - Liao, Q. AU - Moss, K. PY - 2009 DA - 2009// TI - GSK1070916, a potent Aurora B/C kinase inhibitor with broad antitumor activity in tissue culture cells and human tumor xenograft models JO - Mol Cancer Ther. VL - 8 UR - https://doi.org/10.1158/1535-7163.MCT-09-0041 DO - 10.1158/1535-7163.MCT-09-0041 ID - Hardwicke2009 ER -