- CpG enrichment tests show that hyper-methylated CpGs negatively correlated with gene expression are enriched for upstream gene parts, whereas positively correlated CpGs are enriched for the gene body. All three hyper-methylated CpG groups are enriched for informatically determined enhancer elements and experimentally determined differentially methylated regions and DNAse hypersensitive sites. The p values represent hyper-geometric-based over-representation or under-representation and are FDR corrected (significant p values are marked in bold). UTR untranslated region, DMR differentially methylated region
