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Fig. 5 | Breast Cancer Research

Fig. 5

From: Expression and methylation patterns partition luminal-A breast tumors into distinct prognostic subgroups

Fig. 5

Unsupervised analysis of breast cancer tumors using DNA methylation data. Samples were clustered by K-Means based on correlation using the top 2000 variable CpGs over each sample subset. a All 679 tumors. b The 579 samples identified as luminal-A and luminal-B by PAM50 classification. c The 378 luminal A samples only. First bar below each expression matrix shows the assignment of the samples to methylation-based clusters. Second bar (a and b) shows PAM50 calls for the samples. Second bar (c) presents the RNA-Seq based LumA-R1/2 subgroups defined in Figure 3. Right panels show five-year Kaplan-Meier survival plots for the resulting groups

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Breast Cancer Research

ISSN: 1465-542X

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