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Table 4 Risk of interval versus screen-detected cancer according to BMI and mammographic measures

From: Mammographic density and risk of breast cancer by mode of detection and tumor size: a case-control study

  

OPERA (95 % CI)

  

BMI

BMI + DA + NDA

BMI + PDA

BMI + DA

DA + NDA

PDA

DA

All

BIC, AUC

527, 0.60

511, 0.68

508, 0.67

518, 0.65

506, 0.67

504, 0.67

514, 0.64

244 SDC/148 IC

BMI per 1 SD

0.89 (0.73, 1.09)

0.88 (0.71, 1.08)

0.88 (0.72, 1.08)

0.88 (0.72, 1.08)

   
 

DA per adjusted 1 SD

 

1.46 (1.18, 1.82)

 

1.52 (1.22, 1.89)

1.46 (1.17, 1.81)

 

1.51 (1.22, 1.87)

 

PDA per adjusted 1 SD

  

1.76 (1.40,2.23)

  

1.76 (1.39,2.22)

 
 

NDA per adjusted 1 SD

 

0.67 (0.54, 0.83)

  

0.67 (0.54, 0.84)

  

Small tumors

BIC, AUC

321, 0.65

319, 0.70

314, 0.70

320, 0.67

318, 0.68

313, 0.68

321, 0.65

192 SDC/76 IC

BMI per 1 SD

0.67 (0.49, 0.91)

0.72 (0.53, 0.98)

0.72 (0.52, 0.98)

0.68 (0.50, 0.94)

   
 

DA per adjusted 1 SD

 

1.42 (1.05, 1.93)

 

1.46 (1.08, 1.98)

1.45 (1.08, 1.96)

 

1.49 (1.10, 2.01)

 

PDA per adjusted 1 SD

  

1.73 (1.25, 2.39)

  

1.79 (1.30, 2.47)

 
 

NDA per adjusted 1 SD

 

0.69 (0.53, 0.91)

  

0.68 (0.52, 0.89)

  

Large tumors

BIC, AUC

168, 0.57

168, 0.68

166, 0.66

169, 0.63

164, 0.68

161, 0.66

164, 0.63

49 SDC/65 IC

BMI per 1 SD

1.10 (0.78,1.54)

0.98 (0.68, 1.43)

1.01 (0.70, 1.45)

1.04 (0.73, 1.47)

   
 

DA per adjusted 1 SD

 

1.44 (0.96, 2.17)

 

1.48 (1.00, 2.21)

1.44 (0.96, 2.16)

 

1.49 (1.01, 2.21)

 

PDA per adjusted 1 SD

  

1.81 (1.16, 2.83)

  

1.81 (1.16, 2.82)

 
 

NDA per adjusted 1 SD

 

0.57 (0.35, 0.94)

  

0.58 (0.35, 0.94)

  
  1. All of the estimates from unconditional logistic regression were adjusted for age at mammogram and the variables included into the model. AUC area under the receiver operating characteristic curve, BIC Bayesian information criterion, BMI body mass index, CI confidence interval, DA dense area, IC interval cases, NDA non-dense area, OPERA odds per adjusted standard deviation, PDA percent dense area, SD standard deviation, SDC screen-detected cases